The effect of disulphide bond disruption on the barrier integrity of the human nail

A. Baraldi, R.H. Khengar, S. Murdan, M.J. Traynor, S.A. Jones, Marc Brown

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

2 Citations (Scopus)

Abstract

Onychomycosis is the fungal infection of the nail and accounts for approximately 50% of all nail disorders [1]. The prevalence of onychomycosis is increasing and currently up to 10 % of people in the UK and US are reported to be affected by this condition [2,3]. It can be both physically and psychologically debilitating during the most progressive stages of the disease [4,5]. Fungi (most frequently Trichophyton rubrum and Trichophyton mentagrophytes), moulds (Scytalidium spp, Scopulariopsis spp, Fusarium spp, Acremonium spp, Onychocola canadensis) and yeasts (Candida spp) can be co-resident in a diseased nail and hence not every nail can be considered as being populated by the same community of species
Original languageEnglish
Title of host publicationAdvances in Dermatological Sciences
EditorsRobert Chilcott, Keith R. Brain
PublisherRoyal Society of Chemistry
Pages101-112
Number of pages12
Volume1
ISBN (Print)978-1849733984
DOIs
Publication statusPublished - 14 Apr 2014

Publication series

NameIssues in Toxicology
Number20

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