The molecular mystery of neuronal migration: FAK and Cdk5

M. Nikolic

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


The basic building blocks of a cell are its cytoskeletal proteins, the orderly but dynamic organization of which is essential. How signalling molecules regulate the cytoskeleton in the developing nervous system is still largely unknown. A recent breakthrough sheds light on a pathway involving Cdk5 (cyclin-dependent kinase 5) and FAK (focal adhesion kinase), demonstrating their role in regulating microtubule structure and thus nuclear positioning in radially migrating cortical neurones.
Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalTrends in Cell Biology
Issue number1
Publication statusPublished - 2004


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