Transglutaminase Crosslinked Collagen Biomaterial for Medical Implant Materials

M. Griffin; Russell J. Collighan; David Y.S. Chau; E. Verderio Edwards

Transglutaminase Crosslinked Collagen Biomaterial for Medical Implant Materials

M. Griffin (Inventor), Russell J. Collighan (Inventor), David Y.S. Chau (Inventor), E. Verderio Edwards (Inventor)

School of Life and Medical Sciences

Research output: Patent

Abstract

The present invention provides a method for producing an improved biomaterial comprising treating a collagen biomaterial with a transglutaminase under conditions which permit the formation of cross-links within the collagen. Preferably, the transglutaminase is a tissue transglutaminase, a plasma transglutaminase or a microbial transglutaminase. In a preferred embodiment, the collagen biomaterial further comprises a cell adhesion factor, such as fibronectin. The invention further provides biomaterials obtainable by the methods of the invention, and medical implants and wound dressings comprising the same

Original language	English
Patent number	WO2006027622
Publication status	Published - 16 Mar 2006

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@misc{77018f53f78f42d69dd0f4dc754b5282,

title = "Transglutaminase Crosslinked Collagen Biomaterial for Medical Implant Materials",

abstract = "The present invention provides a method for producing an improved biomaterial comprising treating a collagen biomaterial with a transglutaminase under conditions which permit the formation of cross-links within the collagen. Preferably, the transglutaminase is a tissue transglutaminase, a plasma transglutaminase or a microbial transglutaminase. In a preferred embodiment, the collagen biomaterial further comprises a cell adhesion factor, such as fibronectin. The invention further provides biomaterials obtainable by the methods of the invention, and medical implants and wound dressings comprising the same",

author = "M. Griffin and Collighan, {Russell J.} and Chau, {David Y.S.} and {Verderio Edwards}, E.",

year = "2006",

month = mar,

day = "16",

language = "English",

type = "Patent",

note = "WO2006027622",

}

TY - PAT

T1 - Transglutaminase Crosslinked Collagen Biomaterial for Medical Implant Materials

AU - Griffin, M.

AU - Collighan, Russell J.

AU - Chau, David Y.S.

AU - Verderio Edwards, E.

PY - 2006/3/16

Y1 - 2006/3/16

N2 - The present invention provides a method for producing an improved biomaterial comprising treating a collagen biomaterial with a transglutaminase under conditions which permit the formation of cross-links within the collagen. Preferably, the transglutaminase is a tissue transglutaminase, a plasma transglutaminase or a microbial transglutaminase. In a preferred embodiment, the collagen biomaterial further comprises a cell adhesion factor, such as fibronectin. The invention further provides biomaterials obtainable by the methods of the invention, and medical implants and wound dressings comprising the same

AB - The present invention provides a method for producing an improved biomaterial comprising treating a collagen biomaterial with a transglutaminase under conditions which permit the formation of cross-links within the collagen. Preferably, the transglutaminase is a tissue transglutaminase, a plasma transglutaminase or a microbial transglutaminase. In a preferred embodiment, the collagen biomaterial further comprises a cell adhesion factor, such as fibronectin. The invention further provides biomaterials obtainable by the methods of the invention, and medical implants and wound dressings comprising the same

M3 - Patent

M1 - WO2006027622

ER -

Transglutaminase Crosslinked Collagen Biomaterial for Medical Implant Materials

Abstract

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