Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

Xiaoyan Xu; Atheer Awad; Pamela Robles-Martinez; Simon Gaisford; Alvaro Goyanes; Abdul W. Basit

doi:10.1016/j.jconrel.2020.10.008

Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

Xiaoyan Xu
, Atheer Awad
, Pamela Robles-Martinez
, Simon Gaisford
, Alvaro Goyanes
, Abdul W. Basit

Centre for Research into Topical Drug Delivery and Toxicology

Research output: Contribution to journal › Review article › peer-review

349 Citations (Scopus)

Abstract

Three-dimensional (3D) printing is transforming manufacturing paradigms within healthcare. Vat photopolymerization 3D printing technology combines the benefits of high resolution and favourable printing speed, offering a sophisticated approach to fabricate bespoke medical devices and drug delivery systems. Herein, an overview of the vat polymerization techniques, their unique applications in the fields of drug delivery and medical device fabrication, material examples and the advantages they provide within healthcare, is provided. The challenges and drawbacks presented by this technology are also discussed. It is forecast that the adoption of 3D printing could pave the way for a personalised health system, advancing from traditional treatments pathways towards digital healthcare.

Original language	English
Pages (from-to)	743-757
Number of pages	15
Journal	Journal of Controlled Release
Volume	329
DOIs	https://doi.org/10.1016/j.jconrel.2020.10.008
Publication status	Published - 10 Jan 2021

Keywords

3D printed drug products
Additive manufacturing
Personalized pharmaceuticals and medicines
Photopolymerisation
Stereolithographic printing
Stereolithography

Access to Document

10.1016/j.jconrel.2020.10.008

Cite this

@article{7cfb8c2f3b3640f1b573ab1ed22a4ba5,

title = "Vat photopolymerization 3D printing for advanced drug delivery and medical device applications",

abstract = "Three-dimensional (3D) printing is transforming manufacturing paradigms within healthcare. Vat photopolymerization 3D printing technology combines the benefits of high resolution and favourable printing speed, offering a sophisticated approach to fabricate bespoke medical devices and drug delivery systems. Herein, an overview of the vat polymerization techniques, their unique applications in the fields of drug delivery and medical device fabrication, material examples and the advantages they provide within healthcare, is provided. The challenges and drawbacks presented by this technology are also discussed. It is forecast that the adoption of 3D printing could pave the way for a personalised health system, advancing from traditional treatments pathways towards digital healthcare.",

keywords = "3D printed drug products, Additive manufacturing, Personalized pharmaceuticals and medicines, Photopolymerisation, Stereolithographic printing, Stereolithography",

author = "Xiaoyan Xu and Atheer Awad and Pamela Robles-Martinez and Simon Gaisford and Alvaro Goyanes and Basit, \{Abdul W.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2021",

month = jan,

day = "10",

doi = "10.1016/j.jconrel.2020.10.008",

language = "English",

volume = "329",

pages = "743--757",

journal = "Journal of Controlled Release",

issn = "0168-3659",

publisher = "Elsevier",

}

TY - JOUR

T1 - Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

AU - Xu, Xiaoyan

AU - Awad, Atheer

AU - Robles-Martinez, Pamela

AU - Gaisford, Simon

AU - Goyanes, Alvaro

AU - Basit, Abdul W.

PY - 2021/1/10

Y1 - 2021/1/10

N2 - Three-dimensional (3D) printing is transforming manufacturing paradigms within healthcare. Vat photopolymerization 3D printing technology combines the benefits of high resolution and favourable printing speed, offering a sophisticated approach to fabricate bespoke medical devices and drug delivery systems. Herein, an overview of the vat polymerization techniques, their unique applications in the fields of drug delivery and medical device fabrication, material examples and the advantages they provide within healthcare, is provided. The challenges and drawbacks presented by this technology are also discussed. It is forecast that the adoption of 3D printing could pave the way for a personalised health system, advancing from traditional treatments pathways towards digital healthcare.

AB - Three-dimensional (3D) printing is transforming manufacturing paradigms within healthcare. Vat photopolymerization 3D printing technology combines the benefits of high resolution and favourable printing speed, offering a sophisticated approach to fabricate bespoke medical devices and drug delivery systems. Herein, an overview of the vat polymerization techniques, their unique applications in the fields of drug delivery and medical device fabrication, material examples and the advantages they provide within healthcare, is provided. The challenges and drawbacks presented by this technology are also discussed. It is forecast that the adoption of 3D printing could pave the way for a personalised health system, advancing from traditional treatments pathways towards digital healthcare.

KW - 3D printed drug products

KW - Additive manufacturing

KW - Personalized pharmaceuticals and medicines

KW - Photopolymerisation

KW - Stereolithographic printing

KW - Stereolithography

UR - https://www.scopus.com/pages/publications/85094317833

U2 - 10.1016/j.jconrel.2020.10.008

DO - 10.1016/j.jconrel.2020.10.008

M3 - Review article

C2 - 33031881

AN - SCOPUS:85094317833

SN - 0168-3659

VL - 329

SP - 743

EP - 757

JO - Journal of Controlled Release

JF - Journal of Controlled Release

ER -

Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this