Abstract
A 78 year old man presented with acute renal failure following a prolonged respiratory illness. A renal biopsy demonstrated severe suppurative interstitial nephritis with normal glomeruli. After nine weeks of antibiotics he remained anuric and a second biopsy demonstrated pauci-immune, necrotising glomerulonephritis. His subsequent clinical course was consistent with a diagnosis of Wegener's granulomatosis and antineutrophil cytoplasmic antibodies (ANCA) were detected. This is the first reported case of Wegener's granulomatosis presenting with an isolated tubulointerstitial lesion.
| Original language | English |
|---|---|
| Pages (from-to) | 787-9 |
| Number of pages | 3 |
| Journal | Journal of Clinical Pathology |
| Volume | 54 |
| Issue number | 10 |
| Publication status | Published - Oct 2001 |
Keywords
- Acute Disease
- Aged
- Anti-Inflammatory Agents
- Antibodies, Antineutrophil Cytoplasmic
- Antibodies, Antinuclear
- Biopsy
- Cyclophosphamide
- Granulomatosis with Polyangiitis
- Humans
- Immunosuppressive Agents
- Male
- Nephritis, Interstitial
- Prednisone
- Treatment Outcome
- Case Reports
- Journal Article