Research Background
My research interests are focused on studying the neural control of gastrointestinal function. Specifically I wish to understand how processes such as ageing and inflammation affect the organization and function of gastrointestinal sensory neural pathways, and how this impacts upon human health. I use a variety of experimental protocols including electrophysiology, molecular biology, and immunohistochemistry to identify the pathways and characterise the molecules involved in regulating gastrointestinal sensory signalling processes. I have also collaborated with industry to develop biomarkers of gastrointestinal adverse drug reactions for use in safety pharmacology screening procedures.
Membership information:
British Pharmacological Society.
Physiological Society.
Conference Presentations:
Invited lecture presentations:
British Pharmacological Society Meeting Dec 2014
Little Brain Big Brain Meeting, Jeju Island, S. Korea, 2007.
Little Brain Big Brain Meeting, Kenosha USA, 2009.
American Society for Pharmacology and Experimental Therapeutics, Boston, 2013
Distinguished Abstract Plenary Session lecture presentations:
American Gastrointestinal Association, Digestive Disease Week (DDW), Chicago, 2009.
Research Forum lecture presentations:
Infection and Immunity Research Day, University of Sheffield, 2012.
ISAN Meeting, Brazil Sept 2011.
International Symposium on Neurogastroenterology and Motility, Lucerne, SW, 2008 and Jeju Island, S. Korea, 2007.
DDW Meeting, Chicago, 2005; Los Angeles, 2006, San Diego, 2012.
Comparative Invertebrate Physiology and Biochemistry Conference, Calgary, 1999.
Society for Parasitology Conference, Edinburgh, 1995.
Selected Posters presentations/abstracts:
International Symposium on Neurogastroenterology and Motility, Chicago, 2009.
DDW Meeting, Los Angeles, 2006, Washington, 2007 and San Diego, 2008, 2011.
The C. elegans European Meeting, Naples, 2002.
Society for Neuroscience Conference, USA 2001, 1997, 1995.
Funding gained:
BBSRC (co-applicant on research grant with David Grundy) “Sensory dysfunction in the ageing gut” (2009-2012); ~£400,000.
Nuffield Foundation, Research Bursary (2005); £1400.
Physiological Society Vacation Studentships (2005, 2007-2011): £7200.
Distinctions :
Pharmacological Society, Bain Award, 2013.
Physiological Society Travel Awards, 2005; 2007; 2009; 2011, 2013
ISNM 2008 Meeting Abstract Prize winner.
AstraZeneca Science Day 2008, Best Poster Prize.
DDW Meeting 2006, Poster of Distinction Award.
F1000 Biology, recommended paper 2003; “Analysis of G-protein coupled receptors in Caenorhabditis elegans by gene inactivation using RNA mediated genetic interference.”
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Activity: Participating in or organising an event › Participation in workshop, seminar, course
Activity: Participating in or organising an event › Participation in workshop, seminar, course
Activity: Participating in or organising an event › Participation in conference
ID: 1273960
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