University of Hertfordshire

Professor Darragh Murnane PhD BSc (Pharm.) MRPharmS

Professor

Publications

  1. 2021
  2. High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses

    Hoffman, E., Napieralska, P., Mahendran, R., Murnane, D. & Hutter, V., 1 Sep 2021, (E-pub ahead of print) In: Frontiers in Immunology. 12, 611280.

    Research output: Contribution to journalArticlepeer-review

  3. Solid-phase microextraction for assessment of plasma protein binding, a complement to rapid equilibrium dialysis

    Sheelan, A., Baker, D., Murnane, D., Neil, S. & Gerhard, U., 19 Jul 2021, In: Bioanalysis. 13, 14, p. 1101-1111 11 p.

    Research output: Contribution to journalArticlepeer-review

  4. Water Uptake by Evaporating pMDI Aerosol Prior to Inhalation Affects Both Regional and Total Deposition in the Respiratory System

    Legh-Land, V., Haddrell, A. E., Lewis, D., Murnane, D. & Reid, J. P., 24 Jun 2021, In: Pharmaceutics. 13, 7, 22 p., 941.

    Research output: Contribution to journalArticlepeer-review

  5. Crystallographic tomography and molecular modelling of structured organic polycrystalline powders

    Gajjar, P., Nguyen, T. T. H., Sun, J., Styliari, I. D., Bale, H., McDonald, S. A., Burnett, T. L., Tordoff, B., Lauridsen, E., Hammond, R. B., Murnane, D., Withers, P. J. & Roberts, K. J., 2 Mar 2021, (E-pub ahead of print) In: CrystEngComm. 12 p.

    Research output: Contribution to journalArticlepeer-review

  6. The influence of oily vehicle composition and vehicle-membrane interactions on the diffusion of model permeants across barrier membranes

    Najib, O. N., Martin, G. P., Kirton, S. B., Botha, M. J., Sallam, A. S. & Murnane, D., 14 Jan 2021, (E-pub ahead of print) In: Membranes. 11, 1, 17 p., 57.

    Research output: Contribution to journalArticlepeer-review

  7. 2020
  8. Multivariate analytical approaches to identify key molecular properties of vehicles, permeants and membranes that affect permeation through membranes

    Najib, O. N., Kirton, S. B., Martin, G. P., Botha, M. J., Sallam, A. S. & Murnane, D., 31 Oct 2020, In: Pharmaceutics. 12, 10, 18 p., 958.

    Research output: Contribution to journalArticlepeer-review

  9. 3D Characterisation of Dry Powder Inhaler Formulations: Developing X-ray Micro Computed Tomography Approaches

    Gajjar, P., Styliari, I. D., Nguyen, T. T. H., Carr, J., Chen, X., Elliott, J. A., Hammond, R. B., Burnett, T. L., Roberts, K., Withers, P. J. & Murnane, D., Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 32-44 13 p.

    Research output: Contribution to journalArticlepeer-review

  10. A digital workflow from crystallographic structure to single crystal particle attributes for predicting the formulation properties of terbutaline sulfate

    Nguyen, T. T. H., Hammond, R. B., Styliari, I. D., Murnane, D. & Roberts, K. J., 21 May 2020, In: CrystEngComm. 22, 19, p. 3347-3360 14 p.

    Research output: Contribution to journalArticlepeer-review

  11. Unlocking the Microstructure of Inhalation Blends using X-ray Microscopy

    Gajjar, P., Bale, H., Burnett, T., Chen, X., Elliot, J. A., Gomez, H. V., Hammond, R. B., Nguyen, H., Roberts, K. J., Styliari, I. D., Tordoff, B., Withers, P. & Murnane, D., 26 Apr 2020, Respiratory Drug Delivery 2020. Respiratory Drug Delivery, RDD, Vol. 1. p. 101-112 12 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  12. X‐ray Computed Tomography: A 3D method for characterising inhalation powders

    Gajjar, P., Styliari, I. D., Burnett, T., Chen, X., Elliot, J. A., Ganley, W. J., Hammond, R. B., Nguyen, H., Price, R., Roberts, K. J., Withers, P. & Murnane, D., 2 Apr 2020, p. A21-A21. 1 p.

    Research output: Contribution to conferenceAbstractpeer-review

  13. Investigating the suitability of high content image analysis as a tool to assess the reversibility of foamy alveolar macrophage phenotypes in vitro.

    Hoffman, E., Murnane, D. & Hutter, V., 13 Mar 2020, In: Pharmaceutics. 12, 3, 15 p., 262.

    Research output: Contribution to journalArticlepeer-review

  14. Molecular Synthon Modelling Of Inhalation Pharmaceuticals: A Digital Approach To Understanding And Engineering Particle Surface Interactions

    Nguyen, T. T. H., Hammond, R., Styliari, I. D., Murnane, D. & Roberts, K. J., 19 Feb 2020.

    Research output: Contribution to conferencePosterpeer-review

  15. On Measuring the Specific Surface Area of inhalation-grade lactose powders

    Styliari, I. D., Nguyen, T. TH., Gajjar, P., Tordoff, B., Burnett, T., Withers, P., Hammond, R. B., Roberts, K. J. & Murnane, D., 28 Jan 2020.

    Research output: Contribution to conferencePosterpeer-review

  16. 2019
  17. Wurster fluidised bed coating of microparticles: Towards scalable production of oral sustained-release liquid medicines for patients with swallowing difficulties

    Mohylyuk, V., Patel, K., Scott, N., Craig Richardson, Murnane, D. & Liu, F., 11 Nov 2019, In: AAPS PharmSciTech. 21, p. 1-10 10 p., 3.

    Research output: Contribution to journalArticlepeer-review

  18. Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis.

    Bodhaniya, A., Hoffman, E., Ball, D., Klapwijk, J., Steven, R. T., Dexter, A., Bunch, J., Baker, D., Murnane, D., Hutter, V., Page, C., Dailey, L. A. & Forbes, B., 17 Jul 2019, In: Pharmaceutics. 11, 7, 345.

    Research output: Contribution to journalArticlepeer-review

  19. Multiscale Tomography: Probing The Nano-, Micro-, And Meso-Scale Resolution Of Inhalation Powder Structure

    Gajjar, P., Styliari, I. D., Burnett, T., Chen, X., Elliot, J. A., Ganley, W. J., Hammond, R., Nguyen, H., Price, R., Roberts, K., Withers, P. & Murnane, D., 7 May 2019, RDD Europe 2019. Respiratory Drug Delivery, RDD, Vol. 1. p. 155-168 14 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  20. Nano, Micro and Meso-scale characterisation of lactose powders using X-ray Computed Tomography

    Styliari, I. D., Gajjar, P., Burnett, T., Chen, X., Elliott, J. A., Ganley, W. J., Hammond, R., Nguyen, H., Price, R., Roberts, K., Withers, P. & Murnane, D., 4 Apr 2019.

    Research output: Contribution to conferencePoster

  21. 2018
  22. Computational modelling and experimental validation of drug entrainment in a dry powder inhaler

    Kopsch, T., Murnane, D. & Symons, D., 20 Dec 2018, In: International Journal of Pharmaceutics. 553, 1-2, p. 37-46 10 p.

    Research output: Contribution to journalArticlepeer-review

  23. Physicochemical characterisation of inhalation grade lactose after the removal of intrinsic fines

    Styliari, I. D., Mobli, A. & Murnane, D., 14 Dec 2018.

    Research output: Contribution to conferencePosterpeer-review

  24. Solid Phase MicroExtraction (SPME): In Vivo Sampling For Preclinical Drug Development Studies

    Baker, D., Murnane, D., Gerhard, U., Neil, S., White, S. & Scott-Stevens, P., Jun 2018.

    Research output: Contribution to conferencePosterpeer-review

  25. 2017
  26. ‘Great ease and simplicity of action’: Dr Nelson’s Inhaler and the origins of modern inhalation therapy

    Murnane, B., Murnane, D., Sanders, M. & Snell, N., 10 Nov 2017, In: Science Museum Group Journal. 08, 170807.

    Research output: Contribution to journalArticlepeer-review

  27. A personalized medicine approach to the design of dry powder inhalers: Selecting the optimal amount of bypass

    Kopsch, T., Murnane, D. & Symons, D., 30 Aug 2017, In: International Journal of Pharmaceutics. 529, 1-2, p. 589-596 8 p.

    Research output: Contribution to journalArticlepeer-review

  28. Dispersing the Mists: An Experimental History of Medicine Study into the Quality of Volatile Inhalations

    Murnane, B., Gallagher, C., Snell, N., Sanders, M., Moshksar, R. & Murnane, D., 1 Jun 2017, In: Journal of Aerosol Medicine and Pulmonary Drug Delivery. 30, 3, p. 157-163 7 p.

    Research output: Contribution to journalArticlepeer-review

  29. Predicting the Fine Particle Fraction of Dry Powder Inhalers Using Artificial Neural Networks

    Muddle, J., Kirton, S. B., Parisini, I., Muddle, A., Murnane, D., Ali, J., Brown, M., Page, C. & Forbes, B., 1 Jan 2017, In: Journal of Pharmaceutical Sciences. 106, 1, p. 313-321 9 p.

    Research output: Contribution to journalArticlepeer-review

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