University of Hertfordshire

Professor Darragh Murnane PhD BSc (Pharm.) MRPharmS

Professor

Publications

  1. 2020
  2. 3D Characterisation of Dry Powder Inhaler Formulations: Developing X-ray Micro Computed Tomography Approaches

    Gajjar, P., Styliari, I. D., Nguyen, T. T. H., Carr, J., Chen, X., Elliott, J. A., Hammond, R. B., Burnett, T. L., Roberts, K., Withers, P. J. & Murnane, D., Jun 2020, In : European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 32-44 13 p.

    Research output: Contribution to journalArticle

  3. A digital workflow from crystallographic structure to single crystal particle attributes for predicting the formulation properties of terbutaline sulfate

    Nguyen, T. T. H., Hammond, R. B., Styliari, I. D., Murnane, D. & Roberts, K. J., 21 May 2020, In : CrystEngComm. 22, 19, p. 3347-3360 14 p.

    Research output: Contribution to journalArticle

  4. Unlocking the Microstructure of Inhalation Blends using X-ray Microscopy

    Gajjar, P., Bale, H., Burnett, T., Chen, X., Elliot, J. A., Gomez, H. V., Hammond, R. B., Nguyen, H., Roberts, K. J., Styliari, I. D., Tordoff, B., Withers, P. & Murnane, D., 26 Apr 2020, Respiratory Drug Delivery 2020. Respiratory Drug Delivery, RDD, Vol. 1. p. 101-112 12 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  5. X‐ray Computed Tomography: A 3D method for characterising inhalation powders

    Gajjar, P., Styliari, I. D., Burnett, T., Chen, X., Elliot, J. A., Ganley, W. J., Hammond, R. B., Nguyen, H., Price, R., Roberts, K. J., Withers, P. & Murnane, D., 2 Apr 2020, p. A21-A21. 1 p.

    Research output: Contribution to conferenceAbstract

  6. Molecular Synthon Modelling Of Inhalation Pharmaceuticals: A Digital Approach To Understanding And Engineering Particle Surface Interactions

    Nguyen, T. T. H., Hammond, R., Styliari, I. D., Murnane, D. & Roberts, K. J., 19 Feb 2020.

    Research output: Contribution to conferencePoster

  7. On Measuring the Specific Surface Area of inhalation-grade lactose powders

    Styliari, I. D., Nguyen, T. TH., Gajjar, P., Tordoff, B., Burnett, T., Withers, P., Hammond, R. B., Roberts, K. J. & Murnane, D., 28 Jan 2020.

    Research output: Contribution to conferencePoster

  8. 2019
  9. Wurster fluidised bed coating of microparticles: Towards scalable production of oral sustained-release liquid medicines for patients with swallowing difficulties

    Mohylyuk, V., Patel, K., Scott, N., Craig Richardson, Murnane, D. & Liu, F., 11 Nov 2019, In : AAPS PharmSciTech. 21, p. 1-10 10 p., 3.

    Research output: Contribution to journalArticle

  10. Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis.

    Bodhaniya, A., Hoffman, E., Ball, D., Klapwijk, J., Steven, R. T., Dexter, A., Bunch, J., Baker, D., Murnane, D., Hutter, V., Page, C., Dailey, L. A. & Forbes, B., 17 Jul 2019, In : Pharmaceutics. 11, 7, 345.

    Research output: Contribution to journalArticle

  11. Multiscale Tomography: Probing The Nano-, Micro-, And Meso-Scale Resolution Of Inhalation Powder Structure

    Gajjar, P., Styliari, I. D., Burnett, T., Chen, X., Elliot, J. A., Ganley, W. J., Hammond, R., Nguyen, H., Price, R., Roberts, K., Withers, P. & Murnane, D., 7 May 2019, RDD Europe 2019. Respiratory Drug Delivery, RDD, Vol. 1. p. 155-168 14 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  12. Nano, Micro and Meso-scale characterisation of lactose powders using X-ray Computed Tomography

    Styliari, I. D., Gajjar, P., Burnett, T., Chen, X., Elliott, J. A., Ganley, W. J., Hammond, R., Nguyen, H., Price, R., Roberts, K., Withers, P. & Murnane, D., 4 Apr 2019.

    Research output: Contribution to conferencePoster

  13. 2018
  14. Computational modelling and experimental validation of drug entrainment in a dry powder inhaler

    Kopsch, T., Murnane, D. & Symons, D., 20 Dec 2018, In : International Journal of Pharmaceutics. 553, 1-2, p. 37-46 10 p.

    Research output: Contribution to journalArticle

  15. Physicochemical characterisation of inhalation grade lactose after the removal of intrinsic fines

    Styliari, I. D., Mobli, A. & Murnane, D., 14 Dec 2018.

    Research output: Contribution to conferencePoster

  16. 2017
  17. ‘Great ease and simplicity of action’: Dr Nelson’s Inhaler and the origins of modern inhalation therapy

    Murnane, B., Murnane, D., Sanders, M. & Snell, N., 10 Nov 2017, In : Science Museum Group Journal. 08, 170807.

    Research output: Contribution to journalArticle

  18. A personalized medicine approach to the design of dry powder inhalers: Selecting the optimal amount of bypass

    Kopsch, T., Murnane, D. & Symons, D., 30 Aug 2017, In : International Journal of Pharmaceutics. 529, 1-2, p. 589-596 8 p.

    Research output: Contribution to journalArticle

  19. Dispersing the Mists: An Experimental History of Medicine Study into the Quality of Volatile Inhalations

    Murnane, B., Gallagher, C., Snell, N., Sanders, M., Moshksar, R. & Murnane, D., 1 Jun 2017, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 30, 3, p. 157-163 7 p.

    Research output: Contribution to journalArticle

  20. Predicting the Fine Particle Fraction of Dry Powder Inhalers Using Artificial Neural Networks

    Muddle, J., Kirton, S. B., Parisini, I., Muddle, A., Murnane, D., Ali, J., Brown, M., Page, C. & Forbes, B., 1 Jan 2017, In : Journal of Pharmaceutical Sciences. 106, 1, p. 313-321 9 p.

    Research output: Contribution to journalArticle

  21. 2016
  22. Optimizing the Entrainment Geometry of a Dry Powder Inhaler: Methodology and Preliminary Results

    Kopsch, T., Murnane, D. & Symons, D., 1 Nov 2016, In : Pharmaceutical Research. 33, 11, p. 2668-2679 12 p.

    Research output: Contribution to journalArticle

  23. Establishing the importance of oil-membrane interactions on the transmembrane diffusion of physicochemically diverse compounds

    Najib, O. N., Martin, G. P., Kirton, S., Sallam, A-S. & Murnane, D., 15 Jun 2016, In : International Journal of Pharmaceutics. 506, 1-2, p. 429-437 9 p.

    Research output: Contribution to journalArticle

  24. 2015
  25. Interaction of Formulation and Device Factors Determine the In Vitro Performance of Salbutamol Sulphate Dry Powders for Inhalation

    Muddle, J., Murnane, D., Parisini, I., Brown, M., Page, C. & Forbes, B., 1 Nov 2015, In : International Journal of Pharmaceutics. 104, 11, p. 3861-3869 9 p.

    Research output: Contribution to journalArticle

  26. Direct Ionization of Solid-Phase Microextraction Fibers for Quantitative Drug Bionalysis: From Peripheral Circulation to Mass Spectrometry Detection

    Sheelan, A., Michael, T., Neil, S., Murnane, D. & Gerhard, U., 6 Jan 2015, In : Analytical Chemistry. 87, 1, p. 754-759

    Research output: Contribution to journalArticle

  27. Formulation pre-screening of inhalation powders using computational atom-atom systematic search method

    Ramachandran, V., Murnane, D., Hammond, R. B., Pickering, J., Roberts, K. J., Soufian, M., Forbes, B., Jaffari, S., Martin, G. P., Collins, E. & Pencheva, K., 5 Jan 2015, In : Molecular Pharmaceutics. 12, 1, p. 18-33 16 p.

    Research output: Contribution to journalArticle

  28. 2014
  29. Evidence for the existence of powder sub-populations in micronized materials: Aerodynamic size-fractions of aerosolized powders possess distinct physicochemical properties

    Jaffari, S., Forbes, B., Collins, E., Khoo, J., Martin, G. P. & Murnane, D., 31 Dec 2014, In : Pharmaceutical Research. 31, 12, p. 3251-3264

    Research output: Contribution to journalArticle

  30. Potential of a cyclone prototype spacer to improve in vitro dry powder delivery

    Parisini, I., Cheng, S. J., Symons, D. & Murnane, D., May 2014, In : Pharmaceutical Research. 31, 5, p. 1133-1145

    Research output: Contribution to journalArticle

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