University of Hertfordshire

Dr Sharon Rossiter

Publications

  1. 2021
  2. Bicyclic 6-6 Systems: Pteridines

    Rossiter, S. & Ostovar, M., 1 Feb 2021, (E-pub ahead of print) Comprehensive Heterocyclic Chemistry IV. Elsevier, 60 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  3. 2020
  4. Synthesis and in silico modelling of the potential dual mechanistic activity of small cationic peptides potentiating the antibiotic novobiocin against susceptible and multi-drug resistant Escherichia coli

    Passarini, I., Ernesto de Resende, P., Soares, S., Tahmasi, T., Stapleton, P., Malkinson, J., Zloh, M. & Rossiter, S., 30 Nov 2020, In: International Journal of Molecular Sciences. 21, 23, p. 1-19 19 p., 9134.

    Research output: Contribution to journalArticlepeer-review

  5. Discovery of novel small molecule inhibitors of S100P, with in vitro anti-metastatic effects on pancreatic cancer cells

    Camara, R., Ogbeni, D., Gerstmann, L., Ostovar, M., Hurer, E., Scott, M., Mahmoud, N., Radon, T., Crnogorac-Jurcevic, T., Patel, P., Mackenzie, L. S., Chau, D., Kirton, S. & Rossiter, S., 1 Oct 2020, In: European Journal of Medicinal Chemistry. 203, 112621.

    Research output: Contribution to journalArticlepeer-review

  6. 2018
  7. In silico structural evaluation of short cationic antimicrobial peptides

    Passarini, I., Rossiter, S., Malkinson, J. & Zloh, M., 21 Jun 2018, In: Pharmaceutics. 10, 3, 72.

    Research output: Contribution to journalArticlepeer-review

  8. 2017
  9. Anti-Inflammatory Activity of Novel Trans-Stilbene Sulfonamide Analogues as Potential Novel Therapeutic Agents for Lung Disease

    Mahendran, R., Osoba, E., Rossiter, S., Bassin, J., Cook, M. & Hutter, V., 1 Aug 2017, In: Journal of Aerosol Medicine and Pulmonary Drug Delivery. 29, 3, p. A21 65.

    Research output: Contribution to journalMeeting abstractpeer-review

  10. Design, synthesis and in silico evaluation of small cationic peptides with potential antimicrobial activity

    Passarini, I., Rossiter, S., Malkinson, J. & Zloh, M., May 2017, 23rd Lakeland symposium on heterocyclic chemistry.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  11. Synthesis, antimycobacterial activity evaluation and mode of action of series of novel diketones

    Singh, J., Rossiter, S., Bassin, J. & Goyal, M., 25 Apr 2017, Synthesis, antimycobacterial activity evaluation and mode of action of series of novel diketones.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  12. 2016
  13. Anthracene based compounds and their uses

    Rossiter, S., Kirton, S. & Camara, R., 17 Nov 2016, IPC No. C07D 403/04 , Patent No. WO2016/181120, Priority date 8 May 2015

    Research output: Patent

  14. In-silico investigation of RND efflux pumps in multi-drug resistance Gram negative bacteria

    Passarini, I., Rossiter, S., Tahmasi, T., Malkinson, J. & Zloh, M., Nov 2016, Plugging the antibiotics gap: a medicinal chemistry perspective.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  15. NMR and MD simulation studies of two cationic peptides with potential antimicorbial activity

    Passarini, I., Rossiter, S., Scott, M., Malkinson, J. & Zloh, M., Jul 2016, CCPN CCPBioSim joint conference.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  16. Exploring the conformational space of cationic antimicrobial peptides

    Passarini, I., Rossiter, S., Malkinson, J. & Zloh, M., May 2016, RSC Chemical Biology and Bio-organic Chemistry postgraduate symposium.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  17. Exploring the conformational space of cationic antimicrobial peptides

    Passarini, I., Rossiter, S., Zloh, M. & Malkinson, J., Apr 2016, 30th Molecular Modelling Workshop - Erlangen.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  18. 2015
  19. Design, Synthesis and Antimicrobial Evaluation of the in vitro Efficacy of Novel Diketones

    Garikipati, R., Mohammed, O., Rossiter, S., Baines, S., Bassin, J. & Goyal, M., 26 Nov 2015.

    Research output: Contribution to conferencePoster

  20. Synthesis and evaluation of antibacterial activity of series of novel diketones

    Rossiter, S., Zloh, M., Bassin, J., Singh, J. & Goyal, M., 26 Nov 2015.

    Research output: Contribution to conferencePoster

  21. ELISA screen of novel compounds that inhibit S100P and RAGE binding to identify new candidate drugs as a new therapy for pancreatic cancer.

    Ogbeni, D., Camara, R., Chau, D., Kirton, S., Patel, P., MacKenzie, L. & Rossiter, S., 2015, In: pA2 online. 13, 3, 256P.

    Research output: Contribution to journalMeeting abstractpeer-review

  22. 2014
  23. A cellulose-based bioassay for the colorimetric detection of pathogen DNA

    Saikrishnan, D., Goyal, M., Rossiter, S. & Kukol, A., 1 Dec 2014, In: Analytical and Bioanalytical Chemistry. 406, 30, p. 7887-7898

    Research output: Contribution to journalArticlepeer-review

  24. 2012
  25. 2009
  26. Guanidine derivatives as inhibitors of DDAH

    Rossiter, S., Vallance, P., Leiper, J., Selwood, D. & Hartzoulakis, B., 2009, Patent No. US2009069331

    Research output: Patent

  27. 2008
  28. Three heterocyclic rings fused (5:6:5).

    Rossiter, S. & Hilton, S., 2008, Comprehensive Heterocyclic Chemistry III: A Review othe Literature 1995-2007. Katritzky, A., Ramsden, C., Scriven, E. & Taylor, R. (eds.). Elsevier, Vol. 12. p. 711-771

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. 2007
  30. Disruption of methylarginine metabolism impairs vascular homeostasis

    Leiper, J., Nandi, M., Torondel, B., Murray-Rust, J., Malaki, M., O'Hara, B., Rossiter, S., Anthony, S., Madhani, M., Selwood, D., Smith, C., Wojciak-Stothard, B., Rudiger, A., Stidwill, R., McDonald, N. Q. & Vallance, P., Feb 2007, In: Nature Medicine. 13, 2, p. 198-203 6 p.

    Research output: Contribution to journalArticlepeer-review

  31. Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis

    Hartzoulakis, B., Rossiter, S., Gill, H., Steinke, E., Gane, P. J., Hurtado-Guerrero, R., Leiper, J. M., Vallance, P., Murray-Rust, J. & Selwood, D. L., 2007, In: Bioorganic and Medicinal Chemistry Letters. 17, 14, p. 3953-3956

    Research output: Contribution to journalArticlepeer-review

  32. 2005
  33. Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates

    Vallance, P., Bush, H. D., Mok, B. J., Hurtado-Guerrero, R., Gill, H., Rossiter, S., Wilden, J. D. & Caddick, S., 2005, In: Chemical Communications. 44, p. 5563-5565

    Research output: Contribution to journalArticlepeer-review

  34. Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase

    Rossiter, S., Smith, C. L., Malaki, M., Nandi, M., Gill, H., Leiper, J. M., Vallance, P. & Selwood, D. L., 2005, In: Journal of Medicinal Chemistry. 48, 14, p. 4670-4678

    Research output: Contribution to journalArticlepeer-review

  35. Synthesis and anthelmintic properties of arylquinolines with activity against drug resistant nematodes

    Rossiter, S., Peron, J. M., Whitfield, P. J. & Jones, K., 2005, In: Bioorganic and Medicinal Chemistry Letters. 15, 21, p. 4806-4808

    Research output: Contribution to journalArticlepeer-review

  36. 2004
  37. Copper (II) mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries

    Rossiter, S., Woo, C. K., Hartzoulakis, B., Wishart, G., Stanyer, L., Labadie, J. W. & Selwood, D. L., 2004, In: Journal of Combinatorial Chemistry. 6, 3, p. 385-390

    Research output: Contribution to journalArticlepeer-review

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