University of Hertfordshire

Dr Ute Gerhard

Ute Gerhard

Dr Ute Gerhard

Postal address:
University of Hertfordshire, Hatfield, Hertfordshire
United Kingdom

Publications

  1. 2021
  2. Solid-phase microextraction for assessment of plasma protein binding, a complement to rapid equilibrium dialysis

    Sheelan, A., Baker, D., Murnane, D., Neil, S. & Gerhard, U., 19 Jul 2021, In: Bioanalysis. 13, 14, p. 1101-1111 11 p.

    Research output: Contribution to journalArticlepeer-review

  3. 2018
  4. Solid Phase MicroExtraction (SPME): In Vivo Sampling For Preclinical Drug Development Studies

    Baker, D., Murnane, D., Gerhard, U., Neil, S., White, S. & Scott-Stevens, P., Jun 2018.

    Research output: Contribution to conferencePosterpeer-review

  5. 2016
  6. Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives

    Bassin, J., Anagani, B., Benham, C., Goyal, M., Hashemian, M. & Gerhard, U., 23 Jul 2016, In: Molecules. 21, 8, p. 967-979 13 p.

    Research output: Contribution to journalArticlepeer-review

  7. Small molecule recognition of mephedrone using an anthracene molecular clip

    Kellett, K., Broome, J. H., Zloh, M., Kirton, S. B., Fergus, S., Gerhard, U., Stair, J. L. & Wallace, K. J., 16 May 2016, In: Chemical Communications. 52, 47, p. 7474-7477 4 p.

    Research output: Contribution to journalArticlepeer-review

  8. 2015
  9. Direct Ionization of Solid-Phase Microextraction Fibers for Quantitative Drug Bionalysis: From Peripheral Circulation to Mass Spectrometry Detection

    Sheelan, A., Michael, T., Neil, S., Murnane, D. & Gerhard, U., 6 Jan 2015, In: Analytical Chemistry. 87, 1, p. 754-759

    Research output: Contribution to journalArticlepeer-review

  10. The Khat and Meow Meow Tale: Teaching the Relevance of Chemistry through Novel Recreational Drugs

    Fergus, S., Kellett, K. & Gerhard, U., 2015, In: Journal of Chemical Education. 92, 5, p. 843-848

    Research output: Contribution to journalArticlepeer-review

  11. 2006
  12. NK1 antagonists based on seven membered lactam scaffolds

    Elliott, J. M., Carlson, E. J., Chcchi, G. G., Dirat, O., Dominguez, M., Gerhard, U., Jelley, R., Jones, A. B., Kurtz, M. M., Tsao, K. I. & Wheeldon, A., 1 Jun 2006, In: Bioorganic and Medicinal Chemistry Letters. 16, 11, p. 2929-2932 4 p.

    Research output: Contribution to journalArticlepeer-review

  13. 2005
  14. A New Pyridazine Series of GABAA α5 Ligands

    Van Niel, M. B., Wilson, K., Adkins, C. H., Atack, J. R., Castro, J. L., Clarke, D. E., Fletcher, S., Gerhard, U., Mackey, M. M., Malpas, S., Maubach, K., Newman, R., O'Connor, D., Pillai, G. V., Simpson, P. B., Thomas, S. R. & MacLeod, A. M., 22 Sep 2005, In: Journal of Medicinal Chemistry. 48, 19, p. 6004-6011 8 p.

    Research output: Contribution to journalArticlepeer-review

  15. H-1 NMR study of the conformation and absolute stereochemistry of two spirocyclic NK-1 antagonists

    Herbert, R. H., Gerhard, U., Mortishire-Smith, R. J., Thomas, S. R. & Hollingworth, G., Aug 2005, In: Magnetic Resonance in Chemistry. 43, 8, p. 658-661 4 p.

    Research output: Contribution to journalArticlepeer-review

  16. Aryl sulfones: A new class of γ-secretase inhibitors

    Teall, M., Oakley, P., Harrison, T., Shaw, D., Kay, E., Elliott, J., Gerhard, U., Castro, J. L., Shearman, M., Ball, R. G. & Tsou, N. N., 16 May 2005, In: Bioorganic and Medicinal Chemistry Letters. 15, 10, p. 2685-2688 4 p.

    Research output: Contribution to journalArticlepeer-review

  17. Fractionlynx for mass directed purification of metabolites: an alternative tool to get a metabolite into a NMR magnet

    Gunn, D., Kingston, J., Thomas, S. R., Mortishire-Smith, R. J. & Gerhard, U., 2005. 1 p.

    Research output: Contribution to conferencePoster

  18. 2004
  19. Open-access high-resolution mass spectrometry in early drug discovery

    Thomas, S. R. & Gerhard, U., Aug 2004, In: Journal of Mass Spectrometry. 39, 8, p. 942-948 7 p.

    Research output: Contribution to journalArticlepeer-review

  20. 2003
  21. Accelerated metabolite identification by "Extraction-NMR"

    Gerhard, U., Thomas, S. & Mortishire-Smith, R., 14 Jul 2003, In: Journal of Pharmaceutical and Biomedical Analysis. 32, 3, p. 531-538 8 p.

    Research output: Contribution to journalArticlepeer-review

  22. Metabolite identification in drug discovery

    Watt, A. P., Mortishire-Smith, R. J., Gerhard, U. & Thomas, S. R., 1 Jan 2003, In: Current Opinion in Drug Discovery and Development. 6, 1, p. 57-65 9 p.

    Research output: Contribution to journalArticlepeer-review

  23. 2002
  24. Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring

    Gibson, K. R., Hitzel, L., Mortishire-Smith, R. J., Gerhard, U., Jelley, R. A., Reeve, A. J., Rowley, M., Nadin, A. & Owens, A. P., 27 Dec 2002, In: Journal of Organic Chemistry. 67, 26, p. 9354-9360 7 p.

    Research output: Contribution to journalArticlepeer-review

  25. Identification of metabolites of a substance P (NK1 receptor) antagonist in rat hepatocytes and rat plasma

    Hop, C. E. C. A., Wang, Y., Kumar, S., Elipe, M. V. S., Raab, C. E., Dean, D. C., Poon, G. K., Keohane, C-A., Strauss, J., Chiu, S-HL., Curtis, N., Elliott, J., Gerhard, U., Locker, K., Morrison, D., Mortishire-Smith, R., Watt, A. P. & Evans, D. C., 1 Jan 2002, p. 87-88. 2 p.

    Research output: Contribution to conferencePaperpeer-review

  26. Identification of metabolites of a substance P (Neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma

    Hop, C. E. C. A., Wang, Y., Kumar, S., Elipe, M. V. S., Raab, C. E., Dean, D. C., Poon, G. K., Keohane, C-A., Strauss, J., Chiu, S-HL., Curtis, N., Elliott, J., Gerhard, U., Locker, K., Morrison, D., Mortishire-Smith, R., Thomas, S., Watt, A. P. & Evans, D. C., 1 Jan 2002, In: Drug Metabolism and Disposition. 30, 8, p. 937-943 7 p.

    Research output: Contribution to journalArticlepeer-review

  27. 2000
  28. Neighboring group participation of the indole nucleus: An unusual DAST-mediated rearrangerment reaction

    Hallett, D. J., Gerhard, U., Goodacre, S. C., Hitzel, L., Sparey, T. J., Thomas, S., Rowley, M. & Ball, R. G., 11 Aug 2000, In: Journal of Organic Chemistry. 65, 16, p. 4984-4993 10 p.

    Research output: Contribution to journalArticlepeer-review

  29. 1999
  30. Aromatic compounds from the liverwort Plagiochila spinulosa

    Rycroft, D. S., Srivastava, D. L., Cole, W. J., Ifeadike, P., Kimbu, S. F., Singh, J., Connolly, J. D., Thom, C., Gerhard, U., Organ, A. J., Smith, R. J., Hughes, M. & Harrison, L. J., 10 Apr 1999, In: Phytochemistry. 50, 7, p. 1159-1165 7 p.

    Research output: Contribution to journalArticlepeer-review

  31. Neighbouring Group Participation of the Indole Nucleus: An Unusual DAST Mediated Rearrangement Reaction Monitored by Low Temperature NMR Spectroscopy

    Gerhard, U., Goodacre, S. C., Hallett, D. J., Rowley, M., Sparey, T. J. & Thomas, S. R., 1999.

    Research output: Contribution to conferencePoster

  32. 1997
  33. Synthesis of conformationally constrained analogues of BRL32872: Determination of stereochemistry and related pharmacological properties

    Souchet, M., Forest, M-C., Cheval, B., Rouanet, S., Faivre, J-F., Bril, A., Gerhard, U. & Smith, R. J., 5 Aug 1997, In: Bioorganic and Medicinal Chemistry Letters. 7, 15, p. 1989-1994 6 p.

    Research output: Contribution to journalArticlepeer-review

  34. 1995
  35. Ligands which bind weakly to vancomycin: Studies by 13C NMR spectroscopy

    Pearce, C. M., Williams, D. H. & Gerhard, U., 1 Jan 1995, In: Journal of the Chemical Society, Perkin Transactions 2. 1, p. 159-162 4 p.

    Research output: Contribution to journalArticlepeer-review

  36. Two conformers of the glycopeptide antibiotic teicoplanin with distinct ligand binding sites

    Westwell, M. S., Gerhard, U. & Williams, D. H., 1 Jan 1995, In: Journal of Antibiotics. 48, 11, p. 1292-1298 7 p.

    Research output: Contribution to journalArticlepeer-review

  37. Optimisation of a Non-Commercial Loop-Storage Unit and Comparison with Continuous-Flow and Stopped-Flow Experiments in LC-NMR

    Bailey, N. J., Crowe, E. A., Gerhard, U. & Roberts, J. K., 1995.

    Research output: Contribution to conferencePoster

  38. 1994
  39. Dissection of the contributions toward dimerization of glycopeptide antibiotics

    Mackay, J. P., Gerhard, U., Beauregard, D. A., Maplestone, R. A. & Williams, D. H., 1 Jun 1994, In: Journal of the American Chemical Society. 116, 11, p. 4573-4580 8 p.

    Research output: Contribution to journalArticlepeer-review

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