University of Hertfordshire

From the same journal

By the same authors


  • Ling Ren
  • Kaveh Memarzadeh
  • Shuyuan Zhang
  • Ziqing Sun
  • Chunguang Yang
  • Guogang Ren
  • Robert P. Allaker
  • Ke Yang
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Original languageEnglish
Pages (from-to)461-467
Number of pages7
JournalMaterials Science and Engineering C
Early online date17 May 2016
Publication statusPublished - 1 Oct 2016


OBJECTIVE: The aim of this study was to fabricate a novel coping metal CoCrCu alloy using a selective laser melting (SLM) technique with antimicrobial and antibiofilm activities and to investigate its microstructure, mechanical properties, corrosion resistance and biocompatibility.

METHODS: Novel CoCrCu alloy was fabricated using SLM from a mixture of commercial CoCr based alloy and elemental Cu powders. SLM CoCr without Cu served as control. Antibacterial activity was analyzed using standard antimicrobial tests, and antibiofilm properties were investigated using confocal laser scanning microscope. Cu distribution and microstructure were determined using scanning electron microscope, optical microscopy and X-ray diffraction. Corrosion resistance was evaluated by potential dynamic polarization and biocompatibility measured using an MTT assay.

RESULTS: SLM CoCrCu alloys were found to be bactericidal and able to inhibit biofilm formation. Other factors such as microstructure, mechanical properties, corrosion resistance and biocompatibility were similar to those of SLM CoCr alloys.

SIGNIFICANCE: The addition of appropriate amounts of Cu not only maintains normal beneficial properties of CoCr based alloys, but also provides SLM CoCrCu alloys with excellent antibacterial and antibiofilm capabilities. This material has the potential to be used as a coping metal for dental applications.


This document is the Accepted Manuscript version of the following article: Ling Ren, Kaveh Memarzadeh, Shuyuan Zhang, Ziqing Sun, Chunguang Yang, Guogang Ren, Robert T. Allaker, Ke Yang, ‘A novel coping metal material CoCrCu alloy fabricated by selective laser melting with antimicrobial and antibiofilm properties’, Vol. 67: 461-467, October 2016, doi: This manuscript version is made available under the CC-BY-NC-ND 4.0 license .

ID: 10239858