University of Hertfordshire

From the same journal


  • Willem A. M. Wybo
  • Daniele Boccalini
  • Ben Torben-Nielsen
  • Marc-Oliver Gewaltig
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Original languageEnglish
Pages (from-to)2587-2622
JournalNeural Computation
Early online date23 Oct 2015
Publication statusPublished - Dec 2015


We prove that when a class of partial differential equations, generalized from the cable equation, is defined on tree graphs and the inputs are restricted to a spatially discrete, well chosen set of points, the Green's function (GF) formalism can be rewritten to scale as O (n) with the number n of inputs locations, contrary to the previously reported O (n(2)) scaling. We show that the linear scaling can be combined with an expansion of the remaining kernels as sums of exponentials to allow efficient simulations of equations from the aforementioned class. We furthermore validate this simulation paradigm on models of nerve cells and explore its relation with more traditional finite difference approaches. Situations in which a gain in computational performance is expected are discussed.

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