University of Hertfordshire

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By the same authors

An immunocompromised dialysis patient with skin and bone lesions

Research output: Contribution to journalArticle

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  • sfq010

    Final published version, 449 KB, PDF document

  • Miriam Jane Ball
  • Seerapani Gopaluni
  • Suresh Mathavakkannan
  • Michael Brian
  • Ken Farrington
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Original languageEnglish
Pages (from-to)257-259
Number of pages3
JournalNDT Plus
Volume3
Issue3
DOIs
Publication statusPublished - 28 Feb 2010

Abstract

Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory state [1]. Dialysis treatment may further aggravate aspects of this, especially the induction of inflammation. In addition, there is a growing number of patients who have returned to dialysis programmes following transplant failure. Many of these will have been intensively immunosuppressed, often over years or decades. These patients are at particular risk.

ID: 13325249