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Autism spectrum disorders in adult outpatients with obsessive compulsive disorder in the UK. / Wikramanayake, Waduge Nishani Maheshi; Mandy, William; Shahper, Sonia; Kaur, Sukhwinder; Kolli, Sangeetha; Osman, Selma; Reid, Jemma; Jefferies-Sewell, Kiri; Fineberg, Naomi.

In: International Journal of Psychiatry in Clinical Practice, Vol. 22, No. 1, 02.01.2018, p. 54-62.

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Wikramanayake, WNM, Mandy, W, Shahper, S, Kaur, S, Kolli, S, Osman, S, Reid, J, Jefferies-Sewell, K & Fineberg, N 2018, 'Autism spectrum disorders in adult outpatients with obsessive compulsive disorder in the UK', International Journal of Psychiatry in Clinical Practice, vol. 22, no. 1, pp. 54-62. https://doi.org/10.1080/13651501.2017.1354029

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Author

Wikramanayake, Waduge Nishani Maheshi ; Mandy, William ; Shahper, Sonia ; Kaur, Sukhwinder ; Kolli, Sangeetha ; Osman, Selma ; Reid, Jemma ; Jefferies-Sewell, Kiri ; Fineberg, Naomi. / Autism spectrum disorders in adult outpatients with obsessive compulsive disorder in the UK. In: International Journal of Psychiatry in Clinical Practice. 2018 ; Vol. 22, No. 1. pp. 54-62.

Bibtex

@article{e1f8508f0eb14af383579866d9fe328f,
title = "Autism spectrum disorders in adult outpatients with obsessive compulsive disorder in the UK",
abstract = "Objectives: Patients with obsessive compulsive disorder (OCD) frequently show traits of autism spectrum disorders (ASD). This is one of the first studies to explore the clinical impact of the overlap between OCD and ASD as a categorical diagnosis. Methods: A cross-sectional survey in 73 adult outpatients with DSM-IV OCD. Autistic traits were measured using the Autism-Spectrum Quotient (AQ). A clinical estimate ASD diagnosis was made by interview using DSM-IV-TR criteria. OCD patients with and without autistic traits or ASD were compared on demographic and clinical parameters and level of OCD treatment-resistance based on treatment history. Results: Thirty-four (47%) patients scored above the clinical threshold on the AQ (≥26) and 21 (27.8%) met diagnostic criteria for ASD. These diagnoses had not been made before. Patients with autistic traits showed a borderline significant increase in OCD symptom-severity (Yale-Brown Obsessive Compulsive Scale (Y-BOCS); p =.054) and significantly increased impairment of insight (Brown Assessment of Beliefs Scale; p =.01). There was a positive correlation between AQ and Y-BOCS scores (p =.04), but not with OCD treatment resistance. Conclusion: There is a high prevalence of previously undiagnosed ASD in patients with OCD. ASD traits are associated with greater OCD symptom-severity and poor insight.",
keywords = "autism, Autism spectrum disorders, autistic spectrum disorder, autistic traits, co-morbidity, obsessive compulsive disorder",
author = "Wikramanayake, {Waduge Nishani Maheshi} and William Mandy and Sonia Shahper and Sukhwinder Kaur and Sangeetha Kolli and Selma Osman and Jemma Reid and Kiri Jefferies-Sewell and Naomi Fineberg",
year = "2018",
month = jan,
day = "2",
doi = "10.1080/13651501.2017.1354029",
language = "English",
volume = "22",
pages = "54--62",
journal = "International Journal of Psychiatry in Clinical Practice",
issn = "1365-1501",
publisher = "Informa Healthcare",
number = "1",

}

RIS

TY - JOUR

T1 - Autism spectrum disorders in adult outpatients with obsessive compulsive disorder in the UK

AU - Wikramanayake, Waduge Nishani Maheshi

AU - Mandy, William

AU - Shahper, Sonia

AU - Kaur, Sukhwinder

AU - Kolli, Sangeetha

AU - Osman, Selma

AU - Reid, Jemma

AU - Jefferies-Sewell, Kiri

AU - Fineberg, Naomi

PY - 2018/1/2

Y1 - 2018/1/2

N2 - Objectives: Patients with obsessive compulsive disorder (OCD) frequently show traits of autism spectrum disorders (ASD). This is one of the first studies to explore the clinical impact of the overlap between OCD and ASD as a categorical diagnosis. Methods: A cross-sectional survey in 73 adult outpatients with DSM-IV OCD. Autistic traits were measured using the Autism-Spectrum Quotient (AQ). A clinical estimate ASD diagnosis was made by interview using DSM-IV-TR criteria. OCD patients with and without autistic traits or ASD were compared on demographic and clinical parameters and level of OCD treatment-resistance based on treatment history. Results: Thirty-four (47%) patients scored above the clinical threshold on the AQ (≥26) and 21 (27.8%) met diagnostic criteria for ASD. These diagnoses had not been made before. Patients with autistic traits showed a borderline significant increase in OCD symptom-severity (Yale-Brown Obsessive Compulsive Scale (Y-BOCS); p =.054) and significantly increased impairment of insight (Brown Assessment of Beliefs Scale; p =.01). There was a positive correlation between AQ and Y-BOCS scores (p =.04), but not with OCD treatment resistance. Conclusion: There is a high prevalence of previously undiagnosed ASD in patients with OCD. ASD traits are associated with greater OCD symptom-severity and poor insight.

AB - Objectives: Patients with obsessive compulsive disorder (OCD) frequently show traits of autism spectrum disorders (ASD). This is one of the first studies to explore the clinical impact of the overlap between OCD and ASD as a categorical diagnosis. Methods: A cross-sectional survey in 73 adult outpatients with DSM-IV OCD. Autistic traits were measured using the Autism-Spectrum Quotient (AQ). A clinical estimate ASD diagnosis was made by interview using DSM-IV-TR criteria. OCD patients with and without autistic traits or ASD were compared on demographic and clinical parameters and level of OCD treatment-resistance based on treatment history. Results: Thirty-four (47%) patients scored above the clinical threshold on the AQ (≥26) and 21 (27.8%) met diagnostic criteria for ASD. These diagnoses had not been made before. Patients with autistic traits showed a borderline significant increase in OCD symptom-severity (Yale-Brown Obsessive Compulsive Scale (Y-BOCS); p =.054) and significantly increased impairment of insight (Brown Assessment of Beliefs Scale; p =.01). There was a positive correlation between AQ and Y-BOCS scores (p =.04), but not with OCD treatment resistance. Conclusion: There is a high prevalence of previously undiagnosed ASD in patients with OCD. ASD traits are associated with greater OCD symptom-severity and poor insight.

KW - autism

KW - Autism spectrum disorders

KW - autistic spectrum disorder

KW - autistic traits

KW - co-morbidity

KW - obsessive compulsive disorder

UR - http://www.scopus.com/inward/record.url?scp=85027298670&partnerID=8YFLogxK

U2 - 10.1080/13651501.2017.1354029

DO - 10.1080/13651501.2017.1354029

M3 - Article

C2 - 28705096

AN - SCOPUS:85027298670

VL - 22

SP - 54

EP - 62

JO - International Journal of Psychiatry in Clinical Practice

JF - International Journal of Psychiatry in Clinical Practice

SN - 1365-1501

IS - 1

ER -