University of Hertfordshire

From the same journal

  • Niksha Shah
  • David Naseby
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Original languageEnglish
Pages (from-to)1373-1387
JournalJournal of Applied Microbiology
Early online date3 Oct 2014
Publication statusPublished - Nov 2014


Detection of microbial contamination in pharmaceuticals, food and cosmetics has been problematic for several decades. Numerous investigations highlight the urgency for novel methods; development of bioluminescent constructs allows real-time monitoring, rapid analysis and high-throughput screening of products. Microbial growth can be studied by measuring constitutive gene expression. The aim is to develop whole-cell microbial biosensors with Pseudomonas aeruginosa and quantify their growth rate by measuring constitutive expression of lux

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