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Ca2+-in vivo doped biosilica from living Thalassiosira weissflogii diatoms : Investigation on Saos-2 biocompatibility. / Leone, G.; Vona, D.; Lo Presti, M.; Urbano, L.; Cicco, S.; Gristina, R.; Palumbo, F.; Ragni, R.; Farinola, G. M.

In: MRS Advances, Vol. 2, No. 19-20, 16.01.2017, p. 1047-1058.

Research output: Contribution to journalArticlepeer-review

Harvard

Leone, G, Vona, D, Lo Presti, M, Urbano, L, Cicco, S, Gristina, R, Palumbo, F, Ragni, R & Farinola, GM 2017, 'Ca2+-in vivo doped biosilica from living Thalassiosira weissflogii diatoms: Investigation on Saos-2 biocompatibility', MRS Advances, vol. 2, no. 19-20, pp. 1047-1058. https://doi.org/10.1557/adv.2017.49

APA

Leone, G., Vona, D., Lo Presti, M., Urbano, L., Cicco, S., Gristina, R., Palumbo, F., Ragni, R., & Farinola, G. M. (2017). Ca2+-in vivo doped biosilica from living Thalassiosira weissflogii diatoms: Investigation on Saos-2 biocompatibility. MRS Advances, 2(19-20), 1047-1058. https://doi.org/10.1557/adv.2017.49

Vancouver

Author

Leone, G. ; Vona, D. ; Lo Presti, M. ; Urbano, L. ; Cicco, S. ; Gristina, R. ; Palumbo, F. ; Ragni, R. ; Farinola, G. M. / Ca2+-in vivo doped biosilica from living Thalassiosira weissflogii diatoms : Investigation on Saos-2 biocompatibility. In: MRS Advances. 2017 ; Vol. 2, No. 19-20. pp. 1047-1058.

Bibtex

@article{19c56cf019e7444ba5b0b7ea5d65e8c2,
title = "Ca2+-in vivo doped biosilica from living Thalassiosira weissflogii diatoms: Investigation on Saos-2 biocompatibility",
abstract = "Diatoms represent a natural source of mesoporous silica whose applications range from biomedical to photonic fields. Porous hierarchically organized micro structures, the biosilica shells called frustules, can be obtained by removal of the organic biological matter from the unicellular living algae. Diatoms frustules have been investigated as scaffold for bone tissue growth taking advantage of their nanostructured surface and of the possibility to chemically modify the biosilica. Here we report on an easy way to calcium-doped biosilica supports for bone tissue regeneration by in vivo feeding the algae. FTIR and EDX analyses confirmed the incorporation of calcium into the mesopouros biosilica. Cell viability studies showed an ameliorative effect on the Saos-2 cells spreading compared with the cells grown on non-doped biosilica supports.",
keywords = "biomaterial, Ca, nanostructure",
author = "G. Leone and D. Vona and {Lo Presti}, M. and L. Urbano and S. Cicco and R. Gristina and F. Palumbo and R. Ragni and Farinola, {G. M.}",
note = "{\textcopyright} Materials Research Society 2017.",
year = "2017",
month = jan,
day = "16",
doi = "10.1557/adv.2017.49",
language = "English",
volume = "2",
pages = "1047--1058",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "19-20",

}

RIS

TY - JOUR

T1 - Ca2+-in vivo doped biosilica from living Thalassiosira weissflogii diatoms

T2 - Investigation on Saos-2 biocompatibility

AU - Leone, G.

AU - Vona, D.

AU - Lo Presti, M.

AU - Urbano, L.

AU - Cicco, S.

AU - Gristina, R.

AU - Palumbo, F.

AU - Ragni, R.

AU - Farinola, G. M.

N1 - © Materials Research Society 2017.

PY - 2017/1/16

Y1 - 2017/1/16

N2 - Diatoms represent a natural source of mesoporous silica whose applications range from biomedical to photonic fields. Porous hierarchically organized micro structures, the biosilica shells called frustules, can be obtained by removal of the organic biological matter from the unicellular living algae. Diatoms frustules have been investigated as scaffold for bone tissue growth taking advantage of their nanostructured surface and of the possibility to chemically modify the biosilica. Here we report on an easy way to calcium-doped biosilica supports for bone tissue regeneration by in vivo feeding the algae. FTIR and EDX analyses confirmed the incorporation of calcium into the mesopouros biosilica. Cell viability studies showed an ameliorative effect on the Saos-2 cells spreading compared with the cells grown on non-doped biosilica supports.

AB - Diatoms represent a natural source of mesoporous silica whose applications range from biomedical to photonic fields. Porous hierarchically organized micro structures, the biosilica shells called frustules, can be obtained by removal of the organic biological matter from the unicellular living algae. Diatoms frustules have been investigated as scaffold for bone tissue growth taking advantage of their nanostructured surface and of the possibility to chemically modify the biosilica. Here we report on an easy way to calcium-doped biosilica supports for bone tissue regeneration by in vivo feeding the algae. FTIR and EDX analyses confirmed the incorporation of calcium into the mesopouros biosilica. Cell viability studies showed an ameliorative effect on the Saos-2 cells spreading compared with the cells grown on non-doped biosilica supports.

KW - biomaterial

KW - Ca

KW - nanostructure

UR - http://www.scopus.com/inward/record.url?scp=85041636644&partnerID=8YFLogxK

U2 - 10.1557/adv.2017.49

DO - 10.1557/adv.2017.49

M3 - Article

AN - SCOPUS:85041636644

VL - 2

SP - 1047

EP - 1058

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 19-20

ER -