University of Hertfordshire

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Can Kratom (Mitragyna speciosa) Alleviate COVID-19 Pain? A Case Study

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  • Antonio Metastasio
  • Elisabeth Prevete
  • Darshan Singh
  • Oliver Grundmann
  • Walter C. Prozialeck
  • Charles Veltri
  • Giuseppe Bersani
  • Ornella Corazza
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Original languageEnglish
Article number594816
Number of pages6
JournalFrontiers in Psychiatry
Publication statusPublished - 19 Nov 2020


Among the symptoms of COVID-19 fever, general malaise, pain and aches, myalgia, fatigue, and headache can affect the quality of life of patients, even after the end of the acute phase of the infection and can be long lasting. The current treatment of these symptoms, also because COVID-19 patients have been asked not to use non-steroidal anti-inflammatory drugs (NSAIDs), in particular ibuprofen are often unsatisfactory. Among the above mentioned symptoms malaise and fatigue seem the most difficult to treat. In this case report we describe the use of kratom (Mitragyna speciosa) by a patient with confirmed COVID-19 infection. What we observed was a fast and sustained relieve of the above mentioned symptoms.


© 2020 Metastasio, Prevete, Singh, Grundmann, Prozialeck, Veltri, Bersani and Corazza. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY - The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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