University of Hertfordshire

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Original languageEnglish
Pages (from-to)327-330
JournalJournal of Affective Disorders
Publication statusPublished - 2005


In this study, we compared the depressive symptom profile of a group of obsessive compulsive disorder (OCD) patients, with comorbid depression, to a group of patients with major depressive disorder (MDD). The two groups (n = 52 per group) were pair-wise matched on severity of depression as measured by the MÅDRS (mean 24.3 for each group) and we examined between-group differences on the individual MÅDRS item scores. The OCD group was significantly more symptomatic on items 3 (inner tension) and 9 (pessimistic thoughts) and significantly less symptomatic on items 4 (sleep) and 5 (appetite). We discuss these findings in the context of neurobiological bases for the two disorders.


Original article can be found at: Copyright Elsevier Inc. DOI: 10.1016/j.jad.2005.04.004 [Full text of this article is not available in the UHRA]

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