University of Hertfordshire

Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

Research output: Contribution to journalArticlepeer-review


  • G. Mukerji
  • Y. Yiangou
  • S. Corcoran
  • I. S. Selmer
  • G.D. Smith
  • C.D. Benham
  • C. Bountra
  • S. K. Agarwal
  • P. Anand
View graph of relations
Original languageEnglish
Article number6
JournalBMC Urology
Publication statusPublished - 2006


The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of the bladder cooling reflex. In this study, we report the distribution of the cool and menthol receptor TRPM8 in the urinary bladder in patients with overactive and painful bladder syndromes, and its relationship with clinical symptoms.


Original article can be found at : BioMed Central DOI : 10.1186/1471-2490-6-6

ID: 127874