University of Hertfordshire

From the same journal

By the same authors

  • Victoria Shepherd
  • Ishrat Islam
  • Fiona Wood
  • Paula R Williamson
  • Claire Goodman
  • Philip M Bath
  • Carl Thompson
  • Martin Knapp
  • Adam Lee Gordon
  • Kerenza Hood
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Original languageEnglish
JournalBMC Geriatrics
Publication statusAccepted/In press - 29 Apr 2022


People living in care homes have experienced the devastating impact of COVID-19. As interventions to prevent the transmission of COVID-19 are developed and evaluated, there is an urgent need for researchers to agree on the outcomes used when evaluating their effectiveness. To ensure that study results can be compared, a core outcome set (COS) represents the minimum set of outcomes to be measured and reported in condition-specific trials.
To develop a COS for trials assessing the effectiveness of interventions for preventing COVID-19 infection and transmission in care homes.
A list of candidate outcomes was identified by reviewing registered trials for the prevention of COVID-19 in care homes. Seventy key stakeholders participated in a Delphi survey, rating these outcomes on a nine-point scale over two rounds, with the opportunity to propose additional outcomes. Stakeholders included care home representatives (n=19), healthcare professionals (n=20), people with personal experience of care homes (n=7), researchers (n=15) and others (n=9). Outcomes were eligible for inclusion if they met an a priori threshold agreed using established COS methodology. A consensus meeting resulted in agreement of the final outcome set.
Following the Delphi and consensus meeting, twenty-four outcomes were recommended for inclusion across four domains of infection, severity of illness, mortality, and the interventions themselves. However, many outcomes are related thus reducing the measurement burden.
Using a rapid response approach, a COS for COVID-19 prevention interventions in care homes has been developed. Future work should identify instruments for measuring these outcomes.

ID: 26796218