University of Hertfordshire

From the same journal

By the same authors

  • Victoria Shepherd
  • Ishrat Islam
  • Fiona Wood
  • Paula R Williamson
  • Claire Goodman
  • Philip M Bath
  • Carl Thompson
  • Martin Knapp
  • Adam Lee Gordon
  • Kerenza Hood
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Original languageEnglish
JournalBMC Geriatrics
Publication statusAccepted/In press - 29 Apr 2022

Abstract

Background
People living in care homes have experienced the devastating impact of COVID-19. As interventions to prevent the transmission of COVID-19 are developed and evaluated, there is an urgent need for researchers to agree on the outcomes used when evaluating their effectiveness. To ensure that study results can be compared, a core outcome set (COS) represents the minimum set of outcomes to be measured and reported in condition-specific trials.
Objective
To develop a COS for trials assessing the effectiveness of interventions for preventing COVID-19 infection and transmission in care homes.
Methods
A list of candidate outcomes was identified by reviewing registered trials for the prevention of COVID-19 in care homes. Seventy key stakeholders participated in a Delphi survey, rating these outcomes on a nine-point scale over two rounds, with the opportunity to propose additional outcomes. Stakeholders included care home representatives (n=19), healthcare professionals (n=20), people with personal experience of care homes (n=7), researchers (n=15) and others (n=9). Outcomes were eligible for inclusion if they met an a priori threshold agreed using established COS methodology. A consensus meeting resulted in agreement of the final outcome set.
Results
Following the Delphi and consensus meeting, twenty-four outcomes were recommended for inclusion across four domains of infection, severity of illness, mortality, and the interventions themselves. However, many outcomes are related thus reducing the measurement burden.
Conclusion
Using a rapid response approach, a COS for COVID-19 prevention interventions in care homes has been developed. Future work should identify instruments for measuring these outcomes.

ID: 26796218