University of Hertfordshire

Standard

Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design. / Davies, M. J.; Munro, Ian; Tan, Christabel; Tracey, M.C.; Szita, Nicolas.

2014. Paper presented at 4th Micro and Nano Flows Conference, London, United Kingdom.

Research output: Contribution to conferencePaperpeer-review

Harvard

Davies, MJ, Munro, I, Tan, C, Tracey, MC & Szita, N 2014, 'Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design', Paper presented at 4th Micro and Nano Flows Conference, London, United Kingdom, 7/09/14 - 10/09/14.

APA

Davies, M. J., Munro, I., Tan, C., Tracey, M. C., & Szita, N. (2014). Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design. Paper presented at 4th Micro and Nano Flows Conference, London, United Kingdom.

Vancouver

Davies MJ, Munro I, Tan C, Tracey MC, Szita N. Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design. 2014. Paper presented at 4th Micro and Nano Flows Conference, London, United Kingdom.

Author

Davies, M. J. ; Munro, Ian ; Tan, Christabel ; Tracey, M.C. ; Szita, Nicolas. / Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design. Paper presented at 4th Micro and Nano Flows Conference, London, United Kingdom.

Bibtex

@conference{4da4d70a8f3f404bbcb258a9e9c7f025,
title = "Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design",
abstract = "The development of a novel electromagnetically (EM) actuated stirring method, for use in microbioreactors, is reported. Mixing in microbioreactors is critical to ensure even distribution of nutrients to microorganisms and cells. Magnetically driven stirrer bars or peristaltic mixing are the most commonly utilised mixing methods employed in completely liquid-filled microbioreactors. However the circular reactor shape required for mixing with a stirrer bar and frequently used for peristaltically mixed microbioreactors presents difficulties for bubble-free priming in a microfluidic bioreactor. Moreover the circular shape and the hardware required for both types of mixing reduces the potential packing density of multiplexed reactors. We present a new method of mixing, displaying design flexibility by demonstrating mixing in circular and diamond-shaped reactors and a duplex diamond reactor and fermentation of the gram-positive bacteria S. carnosus in a diamond-shaped microbioreactor system. The results of the optimisation of this mixing method for performing fermentations alongside both batch and continuous culture fermentations are presented",
author = "Davies, {M. J.} and Ian Munro and Christabel Tan and M.C. Tracey and Nicolas Szita",
year = "2014",
month = sep,
day = "7",
language = "English",
note = "4th Micro and Nano Flows Conference ; Conference date: 07-09-2014 Through 10-09-2014",

}

RIS

TY - CONF

T1 - Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design

AU - Davies, M. J.

AU - Munro, Ian

AU - Tan, Christabel

AU - Tracey, M.C.

AU - Szita, Nicolas

PY - 2014/9/7

Y1 - 2014/9/7

N2 - The development of a novel electromagnetically (EM) actuated stirring method, for use in microbioreactors, is reported. Mixing in microbioreactors is critical to ensure even distribution of nutrients to microorganisms and cells. Magnetically driven stirrer bars or peristaltic mixing are the most commonly utilised mixing methods employed in completely liquid-filled microbioreactors. However the circular reactor shape required for mixing with a stirrer bar and frequently used for peristaltically mixed microbioreactors presents difficulties for bubble-free priming in a microfluidic bioreactor. Moreover the circular shape and the hardware required for both types of mixing reduces the potential packing density of multiplexed reactors. We present a new method of mixing, displaying design flexibility by demonstrating mixing in circular and diamond-shaped reactors and a duplex diamond reactor and fermentation of the gram-positive bacteria S. carnosus in a diamond-shaped microbioreactor system. The results of the optimisation of this mixing method for performing fermentations alongside both batch and continuous culture fermentations are presented

AB - The development of a novel electromagnetically (EM) actuated stirring method, for use in microbioreactors, is reported. Mixing in microbioreactors is critical to ensure even distribution of nutrients to microorganisms and cells. Magnetically driven stirrer bars or peristaltic mixing are the most commonly utilised mixing methods employed in completely liquid-filled microbioreactors. However the circular reactor shape required for mixing with a stirrer bar and frequently used for peristaltically mixed microbioreactors presents difficulties for bubble-free priming in a microfluidic bioreactor. Moreover the circular shape and the hardware required for both types of mixing reduces the potential packing density of multiplexed reactors. We present a new method of mixing, displaying design flexibility by demonstrating mixing in circular and diamond-shaped reactors and a duplex diamond reactor and fermentation of the gram-positive bacteria S. carnosus in a diamond-shaped microbioreactor system. The results of the optimisation of this mixing method for performing fermentations alongside both batch and continuous culture fermentations are presented

M3 - Paper

T2 - 4th Micro and Nano Flows Conference

Y2 - 7 September 2014 through 10 September 2014

ER -