University of Hertfordshire

Electrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibers

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Electrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibers. / Gutierrez Gonzalez, Javier; Garcia-Cela, Esther; Magan, Naresh; Rahatekar, Sameer.

In: Materials Letters, Vol. 270, 127662, 01.07.2020.

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Gutierrez Gonzalez, Javier ; Garcia-Cela, Esther ; Magan, Naresh ; Rahatekar, Sameer. / Electrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibers. In: Materials Letters. 2020 ; Vol. 270.

Bibtex

@article{10e626aaf8944b338fb5c1323fb38e1b,
title = "Electrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibers",
abstract = "Manufacturing a sodium alginate (SA) and polyethylene oxide (PEO) composite loaded with curcumin (CU) was accomplished in this study by using electrospinning. These composite nanofibers were crosslinked using trifluoroacetic acid (TFA) mechanically characterized along with the morphological properties of the composite nanofiber mesh. We were successful in manufacturing the composite nanofibers with a wide range of CU concentrations ranging from 10 to 40 wt%. Firstly, dissolved in a saturated water/CU solution it was added to SA/PEO blending, homogenized and electrospun. Mechanical properties were affected by both CU addition and the cross-linking process, resulting in a higher ultimate tensile stress (MPa) (from 4.3±2 to 15.1±2 at 10% CU) and Young modulus (GPa) (0.0076±0.003, 0.044±0.003 before and after TFA). CU was successfully encapsulated in the SA nanofibers and excellent mechanical properties were obtained. By using a biocompatible TFA crosslinking and the natural properties of alginate this nanofiber composite could potentially be used for filtering, environmental pollution control, food packaging and for tissue engineering.",
keywords = "Biomedical, Curcumin, Electrospinning, Nanofibers, Sodium alginate",
author = "{Gutierrez Gonzalez}, Javier and Esther Garcia-Cela and Naresh Magan and Sameer Rahatekar",
note = "{\textcopyright} 2020 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/.",
year = "2020",
month = jul,
day = "1",
doi = "10.1016/j.matlet.2020.127662",
language = "English",
volume = "270",
journal = "Materials Letters",
issn = "0167-577X",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Electrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibers

AU - Gutierrez Gonzalez, Javier

AU - Garcia-Cela, Esther

AU - Magan, Naresh

AU - Rahatekar, Sameer

N1 - © 2020 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2020/7/1

Y1 - 2020/7/1

N2 - Manufacturing a sodium alginate (SA) and polyethylene oxide (PEO) composite loaded with curcumin (CU) was accomplished in this study by using electrospinning. These composite nanofibers were crosslinked using trifluoroacetic acid (TFA) mechanically characterized along with the morphological properties of the composite nanofiber mesh. We were successful in manufacturing the composite nanofibers with a wide range of CU concentrations ranging from 10 to 40 wt%. Firstly, dissolved in a saturated water/CU solution it was added to SA/PEO blending, homogenized and electrospun. Mechanical properties were affected by both CU addition and the cross-linking process, resulting in a higher ultimate tensile stress (MPa) (from 4.3±2 to 15.1±2 at 10% CU) and Young modulus (GPa) (0.0076±0.003, 0.044±0.003 before and after TFA). CU was successfully encapsulated in the SA nanofibers and excellent mechanical properties were obtained. By using a biocompatible TFA crosslinking and the natural properties of alginate this nanofiber composite could potentially be used for filtering, environmental pollution control, food packaging and for tissue engineering.

AB - Manufacturing a sodium alginate (SA) and polyethylene oxide (PEO) composite loaded with curcumin (CU) was accomplished in this study by using electrospinning. These composite nanofibers were crosslinked using trifluoroacetic acid (TFA) mechanically characterized along with the morphological properties of the composite nanofiber mesh. We were successful in manufacturing the composite nanofibers with a wide range of CU concentrations ranging from 10 to 40 wt%. Firstly, dissolved in a saturated water/CU solution it was added to SA/PEO blending, homogenized and electrospun. Mechanical properties were affected by both CU addition and the cross-linking process, resulting in a higher ultimate tensile stress (MPa) (from 4.3±2 to 15.1±2 at 10% CU) and Young modulus (GPa) (0.0076±0.003, 0.044±0.003 before and after TFA). CU was successfully encapsulated in the SA nanofibers and excellent mechanical properties were obtained. By using a biocompatible TFA crosslinking and the natural properties of alginate this nanofiber composite could potentially be used for filtering, environmental pollution control, food packaging and for tissue engineering.

KW - Biomedical

KW - Curcumin

KW - Electrospinning

KW - Nanofibers

KW - Sodium alginate

UR - http://www.scopus.com/inward/record.url?scp=85082684284&partnerID=8YFLogxK

U2 - 10.1016/j.matlet.2020.127662

DO - 10.1016/j.matlet.2020.127662

M3 - Article

VL - 270

JO - Materials Letters

JF - Materials Letters

SN - 0167-577X

M1 - 127662

ER -