University of Hertfordshire

Standard

Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking. / Huang, Junjie; Chan, Erica On-Ting; Liu, Xianjing; Lok, Veeleah; Ngai, Chun Ho; Zhang, Lin; Xu, Wanghong; Zheng, Zhi-Jie; Chiu, Peter Ka-Fung; Vasdev, Nikhil; Enikeev, Dmitry; Shariat, Shahrokh F; Ng, Chi Fai; Teoh, Jeremy Yuen-Chun; Wong, Martin C S .

In: Nature Cancer, 03.08.2022.

Research output: Contribution to journalArticlepeer-review

Harvard

Huang, J, Chan, EO-T, Liu, X, Lok, V, Ngai, CH, Zhang, L, Xu, W, Zheng, Z-J, Chiu, PK-F, Vasdev, N, Enikeev, D, Shariat, SF, Ng, CF, Teoh, JY-C & Wong, MCS 2022, 'Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking', Nature Cancer.

APA

Huang, J., Chan, E. O-T., Liu, X., Lok, V., Ngai, C. H., Zhang, L., Xu, W., Zheng, Z-J., Chiu, P. K-F., Vasdev, N., Enikeev, D., Shariat, S. F., Ng, C. F., Teoh, J. Y-C., & Wong, M. C. S. (2022). Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking. Manuscript submitted for publication.

Vancouver

Author

Huang, Junjie ; Chan, Erica On-Ting ; Liu, Xianjing ; Lok, Veeleah ; Ngai, Chun Ho ; Zhang, Lin ; Xu, Wanghong ; Zheng, Zhi-Jie ; Chiu, Peter Ka-Fung ; Vasdev, Nikhil ; Enikeev, Dmitry ; Shariat, Shahrokh F ; Ng, Chi Fai ; Teoh, Jeremy Yuen-Chun ; Wong, Martin C S . / Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking. In: Nature Cancer. 2022.

Bibtex

@article{a5974a4a14264f589345c562f857b927,
title = "Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking",
abstract = "Importance: Prostate cancer is the leading cause of urological malignancy and the second most common cancer in males. Objective: We aimed to examine the global disease burden and trends of prostate cancer incidence and mortality by age, and their associations with gross domestic product (GDP), human development index (HDI), smoking, and alcohol drinking. Design: Trend analysis of global and national cancer registries.Setting: Population-based.Data sources: We retrieved the Global Cancer Observatory (GLOBOCAN) database for the incidence and mortality of prostate cancer in 2020; the World Bank for GDP per capita; the United Nations for HDI; the WHO Global Health Observatory for prevalence of smoking and alcohol drinking; the Cancer Incidence in Five Continents (CI5), WHO mortality database, for trend analysis. Main Outcome Measures: We presented the prostate cancer incidence and mortality using age-standardised rates (ASRs). We examined their associations with GDP, HDI, smoking, and alcohol drinking by Spearman{\textquoteright}s correlations and multivariable regression. We estimated the 10-year trend of incidence and mortality by joinpoint regression analysis with average annual percent change (AAPCs) with 95% confidence intervals (CI) in different age groups.Results: There was a wide variation in the burden of prostate cancer with the highest mortality found in low-income countries while the highest incidence was observed in high-income countries. We found moderate to high positive correlations for GDP, HDI, and alcohol drinking with prostate cancer incidence, whilst a low negative correlation was observed for smoking. Globally, there was an increasing incidence but decreasing mortality of prostate cancer, and such trends were particularly prominent in Europe. Notably, the incidence increase was also found in the younger population aged <50 years. Conclusions and Relevance: There was a global variation in the burden of prostate cancer associated with GDP, HDI, smoking, and alcohol drinking. Prostate cancer had an increasing incidence but decreasing mortality. The increasing incidence of prostate cancer in the younger population is worrying and calls for early action on possible preventive interventions.",
author = "Junjie Huang and Chan, {Erica On-Ting} and Xianjing Liu and Veeleah Lok and Ngai, {Chun Ho} and Lin Zhang and Wanghong Xu and Zhi-Jie Zheng and Chiu, {Peter Ka-Fung} and Nikhil Vasdev and Dmitry Enikeev and Shariat, {Shahrokh F} and Ng, {Chi Fai} and Teoh, {Jeremy Yuen-Chun} and Wong, {Martin C S}",
year = "2022",
month = aug,
day = "3",
language = "English",
journal = "Nature Cancer",
issn = "2662-1347",
publisher = "Nature Research",

}

RIS

TY - JOUR

T1 - Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking

AU - Huang, Junjie

AU - Chan, Erica On-Ting

AU - Liu, Xianjing

AU - Lok, Veeleah

AU - Ngai, Chun Ho

AU - Zhang, Lin

AU - Xu, Wanghong

AU - Zheng, Zhi-Jie

AU - Chiu, Peter Ka-Fung

AU - Vasdev, Nikhil

AU - Enikeev, Dmitry

AU - Shariat, Shahrokh F

AU - Ng, Chi Fai

AU - Teoh, Jeremy Yuen-Chun

AU - Wong, Martin C S

PY - 2022/8/3

Y1 - 2022/8/3

N2 - Importance: Prostate cancer is the leading cause of urological malignancy and the second most common cancer in males. Objective: We aimed to examine the global disease burden and trends of prostate cancer incidence and mortality by age, and their associations with gross domestic product (GDP), human development index (HDI), smoking, and alcohol drinking. Design: Trend analysis of global and national cancer registries.Setting: Population-based.Data sources: We retrieved the Global Cancer Observatory (GLOBOCAN) database for the incidence and mortality of prostate cancer in 2020; the World Bank for GDP per capita; the United Nations for HDI; the WHO Global Health Observatory for prevalence of smoking and alcohol drinking; the Cancer Incidence in Five Continents (CI5), WHO mortality database, for trend analysis. Main Outcome Measures: We presented the prostate cancer incidence and mortality using age-standardised rates (ASRs). We examined their associations with GDP, HDI, smoking, and alcohol drinking by Spearman’s correlations and multivariable regression. We estimated the 10-year trend of incidence and mortality by joinpoint regression analysis with average annual percent change (AAPCs) with 95% confidence intervals (CI) in different age groups.Results: There was a wide variation in the burden of prostate cancer with the highest mortality found in low-income countries while the highest incidence was observed in high-income countries. We found moderate to high positive correlations for GDP, HDI, and alcohol drinking with prostate cancer incidence, whilst a low negative correlation was observed for smoking. Globally, there was an increasing incidence but decreasing mortality of prostate cancer, and such trends were particularly prominent in Europe. Notably, the incidence increase was also found in the younger population aged <50 years. Conclusions and Relevance: There was a global variation in the burden of prostate cancer associated with GDP, HDI, smoking, and alcohol drinking. Prostate cancer had an increasing incidence but decreasing mortality. The increasing incidence of prostate cancer in the younger population is worrying and calls for early action on possible preventive interventions.

AB - Importance: Prostate cancer is the leading cause of urological malignancy and the second most common cancer in males. Objective: We aimed to examine the global disease burden and trends of prostate cancer incidence and mortality by age, and their associations with gross domestic product (GDP), human development index (HDI), smoking, and alcohol drinking. Design: Trend analysis of global and national cancer registries.Setting: Population-based.Data sources: We retrieved the Global Cancer Observatory (GLOBOCAN) database for the incidence and mortality of prostate cancer in 2020; the World Bank for GDP per capita; the United Nations for HDI; the WHO Global Health Observatory for prevalence of smoking and alcohol drinking; the Cancer Incidence in Five Continents (CI5), WHO mortality database, for trend analysis. Main Outcome Measures: We presented the prostate cancer incidence and mortality using age-standardised rates (ASRs). We examined their associations with GDP, HDI, smoking, and alcohol drinking by Spearman’s correlations and multivariable regression. We estimated the 10-year trend of incidence and mortality by joinpoint regression analysis with average annual percent change (AAPCs) with 95% confidence intervals (CI) in different age groups.Results: There was a wide variation in the burden of prostate cancer with the highest mortality found in low-income countries while the highest incidence was observed in high-income countries. We found moderate to high positive correlations for GDP, HDI, and alcohol drinking with prostate cancer incidence, whilst a low negative correlation was observed for smoking. Globally, there was an increasing incidence but decreasing mortality of prostate cancer, and such trends were particularly prominent in Europe. Notably, the incidence increase was also found in the younger population aged <50 years. Conclusions and Relevance: There was a global variation in the burden of prostate cancer associated with GDP, HDI, smoking, and alcohol drinking. Prostate cancer had an increasing incidence but decreasing mortality. The increasing incidence of prostate cancer in the younger population is worrying and calls for early action on possible preventive interventions.

M3 - Article

JO - Nature Cancer

JF - Nature Cancer

SN - 2662-1347

ER -