University of Hertfordshire

From the same journal

By the same authors


Research output: Contribution to journalReview articlepeer-review

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Original languageEnglish
Pages (from-to)429-433
Number of pages5
Publication statusPublished - Jul 2011


The haemodialysis population continues to increase and is becoming more elderly and dependent. Despite major advances in technology, long-term clinical outcomes are disappointing, even in low-risk patients. Current definitions of dialysis adequacy, based on urea clearance, need to be broadened to encompass parameters such as β 2 -microglobulin clearance, salt and water balance, and phosphate control. More frequent treatments may be necessary to adequately control uraemia and can improve survival. Haemodiafiltration provides improved β 2 -microglobulin clearance over haemodialysis, and may improve survival. Failures in access provision, particularly over-dependence on tunnelled lines, contribute significantly to morbidity and excess mortality.

ID: 18280167