University of Hertfordshire

Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population

Research output: Contribution to journalArticlepeer-review

Standard

Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population. / Chiappini, Stephania; Ceci, Franca; Mosca, Alessio; Di Carlo, Francesco; Burkauskas, Julius; Pettorruso, Mauro; Martinotti, Giovanni; Guirguis, Amira; Corkery, John Martin; Scherbaum, Norbert; Schifano, Fabrizio; di Giannantonio, Massimo.

In: Therapeutic Advances in Drug Safety, 29.03.2022.

Research output: Contribution to journalArticlepeer-review

Harvard

Chiappini, S, Ceci, F, Mosca, A, Di Carlo, F, Burkauskas, J, Pettorruso, M, Martinotti, G, Guirguis, A, Corkery, JM, Scherbaum, N, Schifano, F & di Giannantonio, M 2022, 'Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population', Therapeutic Advances in Drug Safety.

APA

Chiappini, S., Ceci, F., Mosca, A., Di Carlo, F., Burkauskas, J., Pettorruso, M., Martinotti, G., Guirguis, A., Corkery, J. M., Scherbaum, N., Schifano, F., & di Giannantonio, M. (Accepted/In press). Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population. Therapeutic Advances in Drug Safety, [TAW-22-01-004].

Vancouver

Chiappini S, Ceci F, Mosca A, Di Carlo F, Burkauskas J, Pettorruso M et al. Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population. Therapeutic Advances in Drug Safety. 2022 Mar 29. TAW-22-01-004.

Author

Chiappini, Stephania ; Ceci, Franca ; Mosca, Alessio ; Di Carlo, Francesco ; Burkauskas, Julius ; Pettorruso, Mauro ; Martinotti, Giovanni ; Guirguis, Amira ; Corkery, John Martin ; Scherbaum, Norbert ; Schifano, Fabrizio ; di Giannantonio, Massimo. / Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population. In: Therapeutic Advances in Drug Safety. 2022.

Bibtex

@article{9f423da936284a4a9f7a810c33dd1486,
title = "Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population",
abstract = "BACKGROUND: During the past decade the misuse of over-the-counter (OTC) medicines has become a global public health concern especially among young people. In this study, we aimed to identify current trends of OTC consumption and related misuse in Italy, exploring the level of knowledge on their diversion and eventual risk factors in the general population.METHODS: The study consisted of an anonymous online survey distributed by direct contact and via the internet between June-November 2021 to the general population living in Italy. Descriptive statistics were reported, and regression analyses were performed to identify risk factors for lifetime misuse of OTC. The study was approved by the University of Hertfordshire (aLMS/SF/UH/02951).RESULTS: A number of 717 subjects responded to the survey and were included in the study. Sample was mainly represented by female (69.3%) students (39.9%) in the 20-25 years age group (30.0%). Based on the survey responses, study participants were divided into two groups according to the presence/absence of OTC abuse/misuse (127 versus 590), which were compared for possible predictors of OTC diversion. Concomitant substances used with OTC were alcohol (8.8%), prescription medicines (6.1%), other OTC (4.7%), and cannabis (2.6%). Multivariate regression showed that the strongest predictor of OTC abuse/misuse was knowledge of the effects of OTC [odds ratio/OR of 2.711, 95% Confidence Interval/CI 1.794-4.097, p<0.001). The probability of OTC abuse/misuse almost doubled when individuals purchased OTC without indication [OR = 1.54, 95% CI 1.02–2.34, p = 0.042]. Finally, education was negatively correlated with OTC abuse/misuse [OR = 0.695, 95% CI 0.58–0.94, p = 0.016].CONCLUSION: Although, according to our data, the phenomenon of OTC abuse appeared to be limited, increasing attention is needed because of its possible underestimation and high-risk outcomes. Preventive strategies, including a simplified access to information, may play a key role in the limitation of OTC drugs misuse. ",
keywords = "over-the-counter drugs, OTC, drug misuse, drug diversion, survey",
author = "Stephania Chiappini and Franca Ceci and Alessio Mosca and {Di Carlo}, Francesco and Julius Burkauskas and Mauro Pettorruso and Giovanni Martinotti and Amira Guirguis and Corkery, {John Martin} and Norbert Scherbaum and Fabrizio Schifano and {di Giannantonio}, Massimo",
year = "2022",
month = mar,
day = "29",
language = "English",
journal = "Therapeutic Advances in Drug Safety",
issn = "2042-0994",
publisher = "SAGE Publications",

}

RIS

TY - JOUR

T1 - Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population

AU - Chiappini, Stephania

AU - Ceci, Franca

AU - Mosca, Alessio

AU - Di Carlo, Francesco

AU - Burkauskas, Julius

AU - Pettorruso, Mauro

AU - Martinotti, Giovanni

AU - Guirguis, Amira

AU - Corkery, John Martin

AU - Scherbaum, Norbert

AU - Schifano, Fabrizio

AU - di Giannantonio, Massimo

PY - 2022/3/29

Y1 - 2022/3/29

N2 - BACKGROUND: During the past decade the misuse of over-the-counter (OTC) medicines has become a global public health concern especially among young people. In this study, we aimed to identify current trends of OTC consumption and related misuse in Italy, exploring the level of knowledge on their diversion and eventual risk factors in the general population.METHODS: The study consisted of an anonymous online survey distributed by direct contact and via the internet between June-November 2021 to the general population living in Italy. Descriptive statistics were reported, and regression analyses were performed to identify risk factors for lifetime misuse of OTC. The study was approved by the University of Hertfordshire (aLMS/SF/UH/02951).RESULTS: A number of 717 subjects responded to the survey and were included in the study. Sample was mainly represented by female (69.3%) students (39.9%) in the 20-25 years age group (30.0%). Based on the survey responses, study participants were divided into two groups according to the presence/absence of OTC abuse/misuse (127 versus 590), which were compared for possible predictors of OTC diversion. Concomitant substances used with OTC were alcohol (8.8%), prescription medicines (6.1%), other OTC (4.7%), and cannabis (2.6%). Multivariate regression showed that the strongest predictor of OTC abuse/misuse was knowledge of the effects of OTC [odds ratio/OR of 2.711, 95% Confidence Interval/CI 1.794-4.097, p<0.001). The probability of OTC abuse/misuse almost doubled when individuals purchased OTC without indication [OR = 1.54, 95% CI 1.02–2.34, p = 0.042]. Finally, education was negatively correlated with OTC abuse/misuse [OR = 0.695, 95% CI 0.58–0.94, p = 0.016].CONCLUSION: Although, according to our data, the phenomenon of OTC abuse appeared to be limited, increasing attention is needed because of its possible underestimation and high-risk outcomes. Preventive strategies, including a simplified access to information, may play a key role in the limitation of OTC drugs misuse.

AB - BACKGROUND: During the past decade the misuse of over-the-counter (OTC) medicines has become a global public health concern especially among young people. In this study, we aimed to identify current trends of OTC consumption and related misuse in Italy, exploring the level of knowledge on their diversion and eventual risk factors in the general population.METHODS: The study consisted of an anonymous online survey distributed by direct contact and via the internet between June-November 2021 to the general population living in Italy. Descriptive statistics were reported, and regression analyses were performed to identify risk factors for lifetime misuse of OTC. The study was approved by the University of Hertfordshire (aLMS/SF/UH/02951).RESULTS: A number of 717 subjects responded to the survey and were included in the study. Sample was mainly represented by female (69.3%) students (39.9%) in the 20-25 years age group (30.0%). Based on the survey responses, study participants were divided into two groups according to the presence/absence of OTC abuse/misuse (127 versus 590), which were compared for possible predictors of OTC diversion. Concomitant substances used with OTC were alcohol (8.8%), prescription medicines (6.1%), other OTC (4.7%), and cannabis (2.6%). Multivariate regression showed that the strongest predictor of OTC abuse/misuse was knowledge of the effects of OTC [odds ratio/OR of 2.711, 95% Confidence Interval/CI 1.794-4.097, p<0.001). The probability of OTC abuse/misuse almost doubled when individuals purchased OTC without indication [OR = 1.54, 95% CI 1.02–2.34, p = 0.042]. Finally, education was negatively correlated with OTC abuse/misuse [OR = 0.695, 95% CI 0.58–0.94, p = 0.016].CONCLUSION: Although, according to our data, the phenomenon of OTC abuse appeared to be limited, increasing attention is needed because of its possible underestimation and high-risk outcomes. Preventive strategies, including a simplified access to information, may play a key role in the limitation of OTC drugs misuse.

KW - over-the-counter drugs

KW - OTC

KW - drug misuse

KW - drug diversion

KW - survey

M3 - Article

JO - Therapeutic Advances in Drug Safety

JF - Therapeutic Advances in Drug Safety

SN - 2042-0994

M1 - TAW-22-01-004

ER -