Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
Microbial Proteomics. / Patel, Hershna; Whitehouse, David.
Genomics and Clinical Diagnostics. ed. / Ralph Rapley; David Whitehouse. The Royal Society of Chemistry, 2019. p. 103-139.Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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TY - CHAP
T1 - Microbial Proteomics
AU - Patel, Hershna
AU - Whitehouse, David
N1 - © Royal Society of Chemistry 2019
PY - 2019/1/29
Y1 - 2019/1/29
N2 - Proteomics is the large-scale and high-throughput study of proteins. A proteome is the population of all proteins expressed by the genome in a specificcell type, tissue or biological fluid at a particular time and under specific conditions. Any tissue, cell type or extracellular fluid is amenable to proteomicanalysis. This chapter addresses the principles and practice of proteomics,focusing on microbial pathogens. An introduction to protein chemistry andanalytical separation techniques is followed by a discussion of the technologies, approaches and applications of proteomics in the microbiology laboratory. Although the potential of proteomics for bacterial identification andcharacterisation remains to be fully realised, it is clear that this rapidly evolving science has already paved the way to aspects of cell biology and molecular pathology that were previously unattainable.
AB - Proteomics is the large-scale and high-throughput study of proteins. A proteome is the population of all proteins expressed by the genome in a specificcell type, tissue or biological fluid at a particular time and under specific conditions. Any tissue, cell type or extracellular fluid is amenable to proteomicanalysis. This chapter addresses the principles and practice of proteomics,focusing on microbial pathogens. An introduction to protein chemistry andanalytical separation techniques is followed by a discussion of the technologies, approaches and applications of proteomics in the microbiology laboratory. Although the potential of proteomics for bacterial identification andcharacterisation remains to be fully realised, it is clear that this rapidly evolving science has already paved the way to aspects of cell biology and molecular pathology that were previously unattainable.
M3 - Chapter (peer-reviewed)
SN - 978-1-78262-821-7
SP - 103
EP - 139
BT - Genomics and Clinical Diagnostics
A2 - Rapley, Ralph
A2 - Whitehouse, David
PB - The Royal Society of Chemistry
ER -