University of Hertfordshire

From the same journal

By the same authors

  • Anthony J Atkin
  • Jason M Lynam
  • Benjamin E Moulton
  • Philip Sawle
  • Roberto Motterlini
  • Nicola M Boyle
  • Mary T Pryce
  • Ian J S Fairlamb
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Original languageEnglish
Pages (from-to)5755-61
Number of pages7
JournalDalton Transactions
Volume40
Issue21
DOIs
Publication statusPublished - 7 Jun 2011

Abstract

The deoxy-myoglobin (deoxy-Mb)/carbonmonoxy-myoglobin (Mb-CO) UV-vis assay is the principal method used for quantifying the rates of CO release from CO-releasing molecules (CO-RMs) that might possess therapeutic benefits. Some issues emerge when the Mb-CO assay is utilized for testing CO-RMs with novel structures, which are comprehensively discussed here for the first time. Two methods for processing raw UV-vis spectroscopic data generated from the assay are presented in this paper.

ID: 13575650