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New/emerging psychoactive substances and associated psychopathological consequences

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New/emerging psychoactive substances and associated psychopathological consequences. / Schifano, Fabrizio; Napoletano, Flavia; Chiappini, Stephania; Guirguis, Amira; Corkery, John; Bonaccorso, Stefania; Ricciardi, Angelo; Scherbaum, Norbert; vento, alessandro.

In: Psychological Medicine, 22.07.2019.

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Schifano, Fabrizio ; Napoletano, Flavia ; Chiappini, Stephania ; Guirguis, Amira ; Corkery, John ; Bonaccorso, Stefania ; Ricciardi, Angelo ; Scherbaum, Norbert ; vento, alessandro. / New/emerging psychoactive substances and associated psychopathological consequences. In: Psychological Medicine. 2019.

Bibtex

@article{5ae40f31e70d43f19c737861ca6f1bf2,
title = "New/emerging psychoactive substances and associated psychopathological consequences",
abstract = "BackgroundThe present paper provides an updated review of both the large number of new/novel/emerging psychoactive substances (NPS) and their associated psychopathological consequences. Focus was here given on identification of those NPS being commented in specialised online sources and the related short-/long-term psychopathological and medical ill-health effects.MethodsNPS have been identified through an innovative crawling/navigating software, called the 'NPS.Finder{\textregistered}', created in order to facilitate the process of early recognition of NPS online. A range of information regarding NPS, including chemical and street names; chemical formula; three-dimensional image and anecdotally reported clinical/psychoactive effects, were here made available.ResultsUsing the 'NPS.Finder{\textregistered}' approach, a few thousand NPS were here preliminarily identified, a number which is about 4-fold higher than those figures suggested by European and international drug agencies. NPS most commonly associated with the onset of psychopathological consequences included here synthetic cannabinoids/cannabimimetics; new synthetic opioids; ketamine-like dissociatives; novel stimulants; novel psychedelics and several prescription and over-the-counter medicines.ConclusionsThe ever-increasing changes in terms of recreational psychotropics' availability represent a relatively new challenge for psychiatry, as the pharmacodynamics and pharmacokinetics of many NPS have not been thoroughly understood. Health/mental health professionals should be informed about the range of NPS; their intake modalities; their psychoactive sought-after effects; the idiosyncratic psychotropics' combinations and finally, their medical and psychopathological risks.",
keywords = "new psychoactive substances (NPS), Psychedelics, drug-induced psychosis, prescribing drug misuse, drug misuse, NPS, psychedelics, Drug-induced psychosis, new psychoactive substances",
author = "Fabrizio Schifano and Flavia Napoletano and Stephania Chiappini and Amira Guirguis and John Corkery and Stefania Bonaccorso and Angelo Ricciardi and Norbert Scherbaum and alessandro vento",
note = "Submitted 24 November 2018, Revised 18 June 2019, Accepted 26 June 2019, Published online 22 July 2019",
year = "2019",
month = jul,
day = "22",
doi = "10.1017/S0033291719001727",
language = "English",
journal = "Psychological Medicine",
issn = "0033-2917",
publisher = "Cambridge University Press",

}

RIS

TY - JOUR

T1 - New/emerging psychoactive substances and associated psychopathological consequences

AU - Schifano, Fabrizio

AU - Napoletano, Flavia

AU - Chiappini, Stephania

AU - Guirguis, Amira

AU - Corkery, John

AU - Bonaccorso, Stefania

AU - Ricciardi, Angelo

AU - Scherbaum, Norbert

AU - vento, alessandro

N1 - Submitted 24 November 2018, Revised 18 June 2019, Accepted 26 June 2019, Published online 22 July 2019

PY - 2019/7/22

Y1 - 2019/7/22

N2 - BackgroundThe present paper provides an updated review of both the large number of new/novel/emerging psychoactive substances (NPS) and their associated psychopathological consequences. Focus was here given on identification of those NPS being commented in specialised online sources and the related short-/long-term psychopathological and medical ill-health effects.MethodsNPS have been identified through an innovative crawling/navigating software, called the 'NPS.Finder®', created in order to facilitate the process of early recognition of NPS online. A range of information regarding NPS, including chemical and street names; chemical formula; three-dimensional image and anecdotally reported clinical/psychoactive effects, were here made available.ResultsUsing the 'NPS.Finder®' approach, a few thousand NPS were here preliminarily identified, a number which is about 4-fold higher than those figures suggested by European and international drug agencies. NPS most commonly associated with the onset of psychopathological consequences included here synthetic cannabinoids/cannabimimetics; new synthetic opioids; ketamine-like dissociatives; novel stimulants; novel psychedelics and several prescription and over-the-counter medicines.ConclusionsThe ever-increasing changes in terms of recreational psychotropics' availability represent a relatively new challenge for psychiatry, as the pharmacodynamics and pharmacokinetics of many NPS have not been thoroughly understood. Health/mental health professionals should be informed about the range of NPS; their intake modalities; their psychoactive sought-after effects; the idiosyncratic psychotropics' combinations and finally, their medical and psychopathological risks.

AB - BackgroundThe present paper provides an updated review of both the large number of new/novel/emerging psychoactive substances (NPS) and their associated psychopathological consequences. Focus was here given on identification of those NPS being commented in specialised online sources and the related short-/long-term psychopathological and medical ill-health effects.MethodsNPS have been identified through an innovative crawling/navigating software, called the 'NPS.Finder®', created in order to facilitate the process of early recognition of NPS online. A range of information regarding NPS, including chemical and street names; chemical formula; three-dimensional image and anecdotally reported clinical/psychoactive effects, were here made available.ResultsUsing the 'NPS.Finder®' approach, a few thousand NPS were here preliminarily identified, a number which is about 4-fold higher than those figures suggested by European and international drug agencies. NPS most commonly associated with the onset of psychopathological consequences included here synthetic cannabinoids/cannabimimetics; new synthetic opioids; ketamine-like dissociatives; novel stimulants; novel psychedelics and several prescription and over-the-counter medicines.ConclusionsThe ever-increasing changes in terms of recreational psychotropics' availability represent a relatively new challenge for psychiatry, as the pharmacodynamics and pharmacokinetics of many NPS have not been thoroughly understood. Health/mental health professionals should be informed about the range of NPS; their intake modalities; their psychoactive sought-after effects; the idiosyncratic psychotropics' combinations and finally, their medical and psychopathological risks.

KW - new psychoactive substances (NPS)

KW - Psychedelics

KW - drug-induced psychosis

KW - prescribing drug misuse

KW - drug misuse

KW - NPS

KW - psychedelics

KW - Drug-induced psychosis

KW - new psychoactive substances

UR - http://www.scopus.com/inward/record.url?scp=85069538323&partnerID=8YFLogxK

U2 - 10.1017/S0033291719001727

DO - 10.1017/S0033291719001727

M3 - Article

JO - Psychological Medicine

JF - Psychological Medicine

SN - 0033-2917

ER -