University of Hertfordshire

From the same journal

By the same authors

  • Beatrice Benatti
  • Bernardo Dell'Osso
  • Hanyang Shen
  • Maria Filippou-Frye
  • Andrea Varias
  • Catherine Sanchez
  • Booil Jo
  • Eric Hollander
  • Dan J. Stein
  • Humberto Nicolini
  • Nuria Lanzagorta
  • Donatella Marazziti
  • Stefano Pallanti
  • Michael Van Ameringen
  • Christine Lochner
  • Oguz Karamustafalioglu
  • Luchezar Hranov
  • Martin Figee
  • Lynne Drummond
  • Jon E. Grant
  • Damiaan Denys
  • Leonardo F. Fontenelle
  • Jose M. Menchon
  • Joseph Zohar
  • Luca Pellegrini
  • Carolyn I. Rodriguez
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Original languageEnglish
Article number357-363
JournalJournal of Psychiatric Research
Volume140
Early online date15 Jun 2021
DOIs
Publication statusE-pub ahead of print - 15 Jun 2021

Abstract

Introduction Obsessive-compulsive disorder (OCD), characterized by repetitive anxiety-inducing intrusive thoughts and compulsive behaviors, is associated with higher suicide ideation and suicide attempts than the general population. This study investigates the prevalence and the correlates of current suicide risk in adult outpatients in an international multisite cross-sectional sample of OCD outpatients. Methods Data were derived from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network's cross-sectional data set (N = 409). Current suicide risk (assessed by Item C of the MINI) and diagnoses of psychiatric disorders were based on DSM-IV. Chi-squared test for categorical variables and t-test for continuous variables were used to make statistical inferences about main features associated with current suicide risk. P < .05 was considered as statistically significant. Results The prevalence of current suicidal risk was 15.9%, with equal likelihood in sociodemographic variables, including age and gender. Increased rates of major depression and generalized anxiety disorder were associated to higher current suicide risk. Current suicide risk was also associated with higher severity of OCD, depressive comorbidity, and higher levels of disability. There were no significant differences in treatment correlates—including type of treatment and psychiatric hospitalizations—between the groups of individuals with and without current suicide risk. Conclusion Our findings suggest that current suicide risk is common in patients with OCD and associated with various forms of pathology. Our work also provides further empirical data to support what is already known clinically: a worse clinical picture characterized by a high severity of OCD, high distress related to obsessions and compulsions, and the presence of comorbidities such as major depression and generalized anxiety disorder should be considered as relevant risk factors for suicide risk.

ID: 25861680