University of Hertfordshire

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Original languageEnglish
Article numberTAH-20-03-015.R1
JournalTherapeutic Advances in Hematology
Publication statusAccepted/In press - 31 Jul 2020

Abstract

Aim: To identify HRQoL issues and symptoms in patients with haematological malignancies (HM) and develop a conceptual framework to reflect the inter-relation between them. Methods: A total of 129 patients with HMs were interviewed in a UK multicentre qualitative study. All interviews were audio recorded, transcribed and analysed using NVivo-11. Results: Overall, 34 issues were reported by patients and were grouped into two parts: quality of life (QoL) and symptoms. The most prevalent HRQoL issues were: ‘eating and drinking habits; social life; physical activity; sleep; and psychological well-being’. Furthermore, most prevalent disease-related symptoms were: tiredness; feeling unwell; breathlessness; lack of energy; and back pain. The most prevalent treatment side effects were: ‘tiredness; feeling sick; disturbance in sense of taste; and breathlessness. Conclusions: Both HMs and their treatments have a significant impact on patients’ HRQoL, in particular on issues such as job role change, body image and impact on finances.

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