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Rapid onsite evaluation uses a very small proportion of total material aspirated at endobronchial or endoscopic ultrasound in the investigation of suspected thoracic malignancy. / Tang, Winnie; Plank, Claire; Kiepura, Claire; Bunting, Sharon; Waugh, Jodie; Coates, Matthew; Spencer, Neil; Barlow, Andrew; Mogal, Rahul; Maddox, Anthony.

In: Cytopathology, Vol. 32, No. 4, 31.07.2021, p. 416-427.

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Tang, Winnie ; Plank, Claire ; Kiepura, Claire ; Bunting, Sharon ; Waugh, Jodie ; Coates, Matthew ; Spencer, Neil ; Barlow, Andrew ; Mogal, Rahul ; Maddox, Anthony. / Rapid onsite evaluation uses a very small proportion of total material aspirated at endobronchial or endoscopic ultrasound in the investigation of suspected thoracic malignancy. In: Cytopathology. 2021 ; Vol. 32, No. 4. pp. 416-427.

Bibtex

@article{92e3b965a59d45cea1a7ca1e18151a2c,
title = "Rapid onsite evaluation uses a very small proportion of total material aspirated at endobronchial or endoscopic ultrasound in the investigation of suspected thoracic malignancy",
abstract = "IntroductionThe objectives were: to measure the proportion of aspirated material used to make direct slides for rapid onsite evaluation (ROSE) at endobronchial (EBUS) and endoscopic ultrasound (EUS) in suspected thoracic malignancy; and to correlate pass weights with ROSE category and needle size.MethodAll EBUS and EUS cases for possible thoracic malignancy October 2018‐May 2019 were included. All material from each pass was expelled into a Petri dish. One drop of material was placed on each of two slides; one used for ROSE, the other fixed and remaining material processed to cell block. Dish and slides were weighed before and after this procedure on a sensitive balance and weight of aspirate and slide material calculated. When ROSE identified malignancy, slide production ceased but target sampling for ancillary studies continued.ResultsROSE accuracy was 96.8%. Mean percentage by target of aspirated material used to make direct slides for ROSE was 1.9% in malignant cases and 3.6% in non‐malignant cases (P = .027 for difference). Mean percentage by pass was 5.9%. Mean weight of a single aspirate was 128.8 mg. Mean weight of aspirates insufficient on ROSE (175.7 mg) was significantly higher than the mean weight of benign or malignant aspirates (117.1 and 114.0 mg, respectively). Mean weight of aspirates using 22G needles (132.6 mg) was significantly higher than that for 25G needles (87.1 mg).ConclusionMaterial made into direct slides at EBUS and EUS and used in part for ROSE uses a tiny proportion of aspirated material with over 98% processed to cell block and available for ancillary testing in malignant cases.",
keywords = "endobronchial ultrasound, rapid on-site evaluation, rapid onsite evaluation, sample weight, specimen handling, thoracic neoplasms",
author = "Winnie Tang and Claire Plank and Claire Kiepura and Sharon Bunting and Jodie Waugh and Matthew Coates and Neil Spencer and Andrew Barlow and Rahul Mogal and Anthony Maddox",
note = "{\textcopyright} 2021 John Wiley & Sons Ltd. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1111/cyt.12963 ",
year = "2021",
month = jul,
day = "31",
doi = "10.1111/cyt.12963",
language = "English",
volume = "32",
pages = "416--427",
journal = "Cytopathology",
issn = "1365-2303",
publisher = "Wiley",
number = "4",

}

RIS

TY - JOUR

T1 - Rapid onsite evaluation uses a very small proportion of total material aspirated at endobronchial or endoscopic ultrasound in the investigation of suspected thoracic malignancy

AU - Tang, Winnie

AU - Plank, Claire

AU - Kiepura, Claire

AU - Bunting, Sharon

AU - Waugh, Jodie

AU - Coates, Matthew

AU - Spencer, Neil

AU - Barlow, Andrew

AU - Mogal, Rahul

AU - Maddox, Anthony

N1 - © 2021 John Wiley & Sons Ltd. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1111/cyt.12963

PY - 2021/7/31

Y1 - 2021/7/31

N2 - IntroductionThe objectives were: to measure the proportion of aspirated material used to make direct slides for rapid onsite evaluation (ROSE) at endobronchial (EBUS) and endoscopic ultrasound (EUS) in suspected thoracic malignancy; and to correlate pass weights with ROSE category and needle size.MethodAll EBUS and EUS cases for possible thoracic malignancy October 2018‐May 2019 were included. All material from each pass was expelled into a Petri dish. One drop of material was placed on each of two slides; one used for ROSE, the other fixed and remaining material processed to cell block. Dish and slides were weighed before and after this procedure on a sensitive balance and weight of aspirate and slide material calculated. When ROSE identified malignancy, slide production ceased but target sampling for ancillary studies continued.ResultsROSE accuracy was 96.8%. Mean percentage by target of aspirated material used to make direct slides for ROSE was 1.9% in malignant cases and 3.6% in non‐malignant cases (P = .027 for difference). Mean percentage by pass was 5.9%. Mean weight of a single aspirate was 128.8 mg. Mean weight of aspirates insufficient on ROSE (175.7 mg) was significantly higher than the mean weight of benign or malignant aspirates (117.1 and 114.0 mg, respectively). Mean weight of aspirates using 22G needles (132.6 mg) was significantly higher than that for 25G needles (87.1 mg).ConclusionMaterial made into direct slides at EBUS and EUS and used in part for ROSE uses a tiny proportion of aspirated material with over 98% processed to cell block and available for ancillary testing in malignant cases.

AB - IntroductionThe objectives were: to measure the proportion of aspirated material used to make direct slides for rapid onsite evaluation (ROSE) at endobronchial (EBUS) and endoscopic ultrasound (EUS) in suspected thoracic malignancy; and to correlate pass weights with ROSE category and needle size.MethodAll EBUS and EUS cases for possible thoracic malignancy October 2018‐May 2019 were included. All material from each pass was expelled into a Petri dish. One drop of material was placed on each of two slides; one used for ROSE, the other fixed and remaining material processed to cell block. Dish and slides were weighed before and after this procedure on a sensitive balance and weight of aspirate and slide material calculated. When ROSE identified malignancy, slide production ceased but target sampling for ancillary studies continued.ResultsROSE accuracy was 96.8%. Mean percentage by target of aspirated material used to make direct slides for ROSE was 1.9% in malignant cases and 3.6% in non‐malignant cases (P = .027 for difference). Mean percentage by pass was 5.9%. Mean weight of a single aspirate was 128.8 mg. Mean weight of aspirates insufficient on ROSE (175.7 mg) was significantly higher than the mean weight of benign or malignant aspirates (117.1 and 114.0 mg, respectively). Mean weight of aspirates using 22G needles (132.6 mg) was significantly higher than that for 25G needles (87.1 mg).ConclusionMaterial made into direct slides at EBUS and EUS and used in part for ROSE uses a tiny proportion of aspirated material with over 98% processed to cell block and available for ancillary testing in malignant cases.

KW - endobronchial ultrasound

KW - rapid on-site evaluation

KW - rapid onsite evaluation

KW - sample weight

KW - specimen handling

KW - thoracic neoplasms

UR - http://www.scopus.com/inward/record.url?scp=85103121890&partnerID=8YFLogxK

U2 - 10.1111/cyt.12963

DO - 10.1111/cyt.12963

M3 - Article

VL - 32

SP - 416

EP - 427

JO - Cytopathology

JF - Cytopathology

SN - 1365-2303

IS - 4

ER -