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The e-psychonauts’ ‘Spiced’ World; assessment of the synthetic cannabinoids’ information available online. / Zangani, Caroline; Schifano, Fabrizio; Napoletano, Flavia; Arillotta, Davide; Gilgar, Liam; Guirguis, Amira; Corkery, John Martin; Gambini, Orsola; Vento, Alessandro.

In: Current neuropharmacology, Vol. 18, No. 10, 02.03.2020, p. 966-1051.

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Zangani, Caroline ; Schifano, Fabrizio ; Napoletano, Flavia ; Arillotta, Davide ; Gilgar, Liam ; Guirguis, Amira ; Corkery, John Martin ; Gambini, Orsola ; Vento, Alessandro. / The e-psychonauts’ ‘Spiced’ World; assessment of the synthetic cannabinoids’ information available online. In: Current neuropharmacology. 2020 ; Vol. 18, No. 10. pp. 966-1051.

Bibtex

@article{f0b765a6ed3e40619d2df2b9d3da9bc9,
title = "The e-psychonauts{\textquoteright} {\textquoteleft}Spiced{\textquoteright} World; assessment of the synthetic cannabinoids{\textquoteright} information available online",
abstract = "Background: A wide range of novel psychoactive substances (NPS) is regularly searched and discussed online by web-based drug enthusiasts (i.e. the e-psychonauts). Among NPS, the range of synthetic cannabinoids (SC; {\textquoteleft}Spice{\textquoteright}) currently represents a challenge for governments and clinicians. Methods: Using a web crawler (i.e. the NPS.Finder{\textregistered}), the present study aimed at assessing psychonauts{\textquoteright} fora/platforms to better understand the online mentions of SC. Results: The open-web crawling/navigating software identified here some 1,103 synthetic cannabinoids. Of these, 863 molecules were not listed in either the international or the European NPS databases. Conclusion: A web crawling approach helped here in identifying a large range of unknown SC likely to possess a misuse potential. Most of these novel/emerging molecules are still relatively unknown. This is a reason for concern; each of these analogues potentially presents different toxicodynamic profiles and there is a lack of docking, preclinical, and clinical observations. Strengthening multidisciplinary collaboration between clinicians and bioinformatics may prove useful in better assessing SC-associated public health risks.",
keywords = "psychonauts, NPS, new psychoactive substances, synthetic cannabinoids, web crawling, Web crawling, Synthetic cannabinoids, New psychoactive substances, Psychonauts",
author = "Caroline Zangani and Fabrizio Schifano and Flavia Napoletano and Davide Arillotta and Liam Gilgar and Amira Guirguis and Corkery, {John Martin} and Orsola Gambini and Alessandro Vento",
note = "{\textcopyright} 2020 Bentham Science. This is the accepted manuscript version of an article which has been published in final form at https://dx.doi.org/10.2174/1570159X18666200302125146.",
year = "2020",
month = mar,
day = "2",
doi = "10.2174/1570159X18666200302125146",
language = "English",
volume = "18",
pages = "966--1051",
journal = "Current neuropharmacology",
issn = "1570-159X",
publisher = "Bentham Science Publishers B.V.",
number = "10",

}

RIS

TY - JOUR

T1 - The e-psychonauts’ ‘Spiced’ World; assessment of the synthetic cannabinoids’ information available online

AU - Zangani, Caroline

AU - Schifano, Fabrizio

AU - Napoletano, Flavia

AU - Arillotta, Davide

AU - Gilgar, Liam

AU - Guirguis, Amira

AU - Corkery, John Martin

AU - Gambini, Orsola

AU - Vento, Alessandro

N1 - © 2020 Bentham Science. This is the accepted manuscript version of an article which has been published in final form at https://dx.doi.org/10.2174/1570159X18666200302125146.

PY - 2020/3/2

Y1 - 2020/3/2

N2 - Background: A wide range of novel psychoactive substances (NPS) is regularly searched and discussed online by web-based drug enthusiasts (i.e. the e-psychonauts). Among NPS, the range of synthetic cannabinoids (SC; ‘Spice’) currently represents a challenge for governments and clinicians. Methods: Using a web crawler (i.e. the NPS.Finder®), the present study aimed at assessing psychonauts’ fora/platforms to better understand the online mentions of SC. Results: The open-web crawling/navigating software identified here some 1,103 synthetic cannabinoids. Of these, 863 molecules were not listed in either the international or the European NPS databases. Conclusion: A web crawling approach helped here in identifying a large range of unknown SC likely to possess a misuse potential. Most of these novel/emerging molecules are still relatively unknown. This is a reason for concern; each of these analogues potentially presents different toxicodynamic profiles and there is a lack of docking, preclinical, and clinical observations. Strengthening multidisciplinary collaboration between clinicians and bioinformatics may prove useful in better assessing SC-associated public health risks.

AB - Background: A wide range of novel psychoactive substances (NPS) is regularly searched and discussed online by web-based drug enthusiasts (i.e. the e-psychonauts). Among NPS, the range of synthetic cannabinoids (SC; ‘Spice’) currently represents a challenge for governments and clinicians. Methods: Using a web crawler (i.e. the NPS.Finder®), the present study aimed at assessing psychonauts’ fora/platforms to better understand the online mentions of SC. Results: The open-web crawling/navigating software identified here some 1,103 synthetic cannabinoids. Of these, 863 molecules were not listed in either the international or the European NPS databases. Conclusion: A web crawling approach helped here in identifying a large range of unknown SC likely to possess a misuse potential. Most of these novel/emerging molecules are still relatively unknown. This is a reason for concern; each of these analogues potentially presents different toxicodynamic profiles and there is a lack of docking, preclinical, and clinical observations. Strengthening multidisciplinary collaboration between clinicians and bioinformatics may prove useful in better assessing SC-associated public health risks.

KW - psychonauts

KW - NPS

KW - new psychoactive substances

KW - synthetic cannabinoids

KW - web crawling

KW - Web crawling

KW - Synthetic cannabinoids

KW - New psychoactive substances

KW - Psychonauts

UR - http://www.scopus.com/inward/record.url?scp=85090874908&partnerID=8YFLogxK

U2 - 10.2174/1570159X18666200302125146

DO - 10.2174/1570159X18666200302125146

M3 - Review article

VL - 18

SP - 966

EP - 1051

JO - Current neuropharmacology

JF - Current neuropharmacology

SN - 1570-159X

IS - 10

ER -