University of Hertfordshire

Treatment of calcified coronary artery lesions

Research output: Contribution to journalReview articlepeer-review

  • Mohamed Farag
  • Charis Costopoulos
  • Diana A Gorog
  • Abhiram Prasad
  • Manivannan Srinivasan
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Original languageEnglish
Pages (from-to)683-690
Number of pages8
JournalExpert review of cardiovascular therapy
Early online date15 Mar 2016
Publication statusE-pub ahead of print - 15 Mar 2016


Heavily calcified coronary plaques represent a complex lesion subset and a challenge to the interventional cardiologist, as they are often resistant to simple plaque modification with conventional balloon angioplasty. Inadequate plaque modification can lead to stent underdeployment, which itself predisposes to in-stent restenosis and stent thrombosis. Over the years, a number of mechanical devices ranging from modified angioplasty balloons to atherectomy devices have become available in order to tackle such lesions. Here we review these devices concentrating on the evidence behind their use.

ID: 13239881